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About: ●. GRADEing the certainty of the available evidence is more important than ever because of the unprecedented pressure for action and the large number of people affected by decisions; ●. The GRADE approach is a transparent and structured method for assessing the certainty of evidence and when developing recommendations that requires little additional time; ●. In situations of emergencies and urgencies, such as the COVID-19 pandemic, GRADE can similarly be used to express and convey certainty in intervention effects, test accuracy, risk and prognostic factors, consequences of public health measures, and qualitative bodies of evidence; ●. Requirements for emergency, urgency, rapid and routine GRADE assessment may differ but should transition from one to another.

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