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  • Abstract Patients with immunodeficiencies or some types of autoimmune diseases rely on a safe therapy with intravenous immunoglobulins (IVIGs) manufactured from human plasma, the only available source for this therapeutic. Since plasma is predisposed to contamination by a variety of blood-borne pathogens, ascertaining and ensuring the pathogen safety of plasma-derived therapeutics is a priority among manufacturers. State-of-the-art manufacturing processes provide a high safety standard by incorporating virus elimination procedures into the manufacturing process. Based on their mechanism these procedures are grouped into three classes: partitioning, inactivation, and virusfiltration.
Subject
  • Virology
  • Autoimmune diseases
  • Infectious diseases
  • Transfusion medicine
  • Gases
  • Concepts in physics
  • Plasma physics
  • RTT
  • Phases of matter
  • Astrophysics
  • Electrical conductors
  • Subfields of physics
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