About: Osteonecrosis of the jaw   Goto Sponge  NotDistinct  Permalink

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Osteonecrosis of the jaw (ONJ) is a severe bone disease (osteonecrosis) that affects the jaws (the maxilla and the mandible). Various forms of ONJ have been described since 1861, and a number of causes have been suggested in the literature. Treatment options have been explored; however, severe cases of ONJ still require surgical removal of the affected bone. A thorough history and assessment of pre-existing systemic problems and possible sites of dental infection are required to help prevent the condition, especially if bisphosphonate therapy is considered.

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  • Osteonecrosis of the jaw
  • Ostéonécrose du maxillaire
  • Martwica kości szczęki i żuchwy
  • Osteonecrosi della mascella
  • النخر العظمي في الفك
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  • L’ostéonécrose de la mâchoire est une maladie sévère de l’os qui atteint la mâchoire, c’est-à-dire les maxillaires et la mandibule. Les lésions osseuses et la nécrose surviennent à la suite d'une réduction de l'apport sanguin local (ischémie). Cette affection entre donc dans la catégorie générale des nécroses ischémiques ou ostéonécrose avasculaire (littéralement « mort osseuse par insuffisance circulatoire »). Diverses formes d’ostéonécrose de la mâchoire ont été décrites au cours des 160 dernières années, et un certain nombre de causes ont été énumérées dans la littérature.
  • Martwica kości szczęki i żuchwy, osteonekroza szczęki i żuchwy, ONJ (od ang. osteonecrosis of the jaw) – rzadkie schorzenie charakteryzujące się klinicznie odsłonięciem obszaru kości żuchwy, szczęki i/lub podniebienia, niegojącym lub źle gojącym się przez 6–8 tygodni.
  • النخر العظمي في الفك (ONJ) هو مرض حاد في العظام (تنخر عظمي) يصيب الفكين (الفك العلوي والفك السفلي). وُصفت أشكال مختلفة من المرض على مدار 160 عامًا الماضية. اقتُرحت العديد من الأسباب في الأدبيات الطبية. عُرّف النخر العظمي للفك المرتبط بأدوية البيفوسفونات، والموجود في بعض أنظمة علاج السرطان، على أنه حالة مرضية (تنخر عظم الفك المرتبط بالبيسفوسفونات) منذ عام 2003. ما تزال المخاطر المحتملة من الجرعات الفموية المنخفضة من البيفوسفونات، التي يأخذها المرضى لمنع أو علاج هشاشة العظام، غير مؤكدة.
  • Osteonecrosis of the jaw (ONJ) is a severe bone disease (osteonecrosis) that affects the jaws (the maxilla and the mandible). Various forms of ONJ have been described since 1861, and a number of causes have been suggested in the literature. Treatment options have been explored; however, severe cases of ONJ still require surgical removal of the affected bone. A thorough history and assessment of pre-existing systemic problems and possible sites of dental infection are required to help prevent the condition, especially if bisphosphonate therapy is considered.
  • L'osteonecrosi della mascella (ONJ) è una grave malattia ossea (osteonecrosi che colpisce le mascelle (mascella e mandibola). Varie forme di ONJ sono state descritte negli ultimi 160 anni e in letteratura sono state suggerite numerose cause. L'osteonecrosi della mandibola è spesso associata alla terapia con bifosfonati, necessaria per trattare alcune tipologie di cancro, e dal 2003 è stata identificata e definita come una vera e propria condizione patologica (osteonecrosi della mandibola associata a bisfosfonati).
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  • Osteonecrosis of the jaws
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  • Osteonecrosis of the jaws
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