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Lupus band test is done upon skin biopsy, with direct immunofluorescence staining, in which, if positive, IgG and depositions are found at the dermoepidermal junction. This test can be helpful in distinguishing systemic lupus erythematosus (SLE) from cutaneous lupus, because in SLE the lupus band test will be positive in both involved and uninvolved skin, whereas with cutaneous lupus only the involved skin will be positive. The minimum criteria for positivity are:

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  • Lupus band test
  • Lupusa strio-testo
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  • Lupus band test is done upon skin biopsy, with direct immunofluorescence staining, in which, if positive, IgG and depositions are found at the dermoepidermal junction. This test can be helpful in distinguishing systemic lupus erythematosus (SLE) from cutaneous lupus, because in SLE the lupus band test will be positive in both involved and uninvolved skin, whereas with cutaneous lupus only the involved skin will be positive. The minimum criteria for positivity are:
  • Lupusa strio-testo (LST) estas biopsio de nedamaĝita haŭto ĉe supra triono de la ŝultro kun posta imunohistokemia esplorado kun difinado de , , kaj komponantoj de la komplemento C3, C1q. LST povas esti uzata por frua diagnozado de lupuso ĉe pacientoj sen haŭtaj simptomoj kaj kaze de eventuala lupuso.
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  • Lupus band test
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  • Lupusa strio-testo (LST) estas biopsio de nedamaĝita haŭto ĉe supra triono de la ŝultro kun posta imunohistokemia esplorado kun difinado de , , kaj komponantoj de la komplemento C3, C1q. LST povas esti uzata por frua diagnozado de lupuso ĉe pacientoj sen haŭtaj simptomoj kaj kaze de eventuala lupuso.
  • Lupus band test is done upon skin biopsy, with direct immunofluorescence staining, in which, if positive, IgG and depositions are found at the dermoepidermal junction. This test can be helpful in distinguishing systemic lupus erythematosus (SLE) from cutaneous lupus, because in SLE the lupus band test will be positive in both involved and uninvolved skin, whereas with cutaneous lupus only the involved skin will be positive. The minimum criteria for positivity are: * In sun-exposed skin: presence of a band of deposits of IgM along the epidermal basement membrane in 50% of the biopsy, intermediate (2+) intensity or more. * In sun-protected skin : presence of interrupted (i.e. less than 50%) deposits of IgM along the epidermal basement membrane, intermediate (2+) intensity or more. The presence of other immunoglobulins (especially IgA) and/or complement proteins (especially C4) increases the specificity of a positive test.
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  • Microphotograph of a histological section of human skin prepared for direct immunofluorescence using an anti-IgG antibody. The skin is from a person with systemic lupus erythematosus and shows IgG deposits at two different places: The first is a bandlike deposit along the epidermal basement membrane ; the second is within the nuclei of the epidermal cells .
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  • distinguish different types of lupus
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