About: Canagliflozin

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An Entity of Type : yago:WikicatAnti-diabeticDrugs, within Data Space : covidontheweb.inria.fr associated with source document(s)

Canagliflozin, sold under the brand name Invokana among others, is a medication used to treat type 2 diabetes. It is a third-line medication to be tried after metformin, a first-line medication for type 2 diabetes. It is used together with exercise and diet. It is not recommended in type 1 diabetes. It is taken by mouth.

Attributes	Values
type	Thing entity matter drug yago:Abstraction100002137 yago:CausalAgent100007347 yago:PhysicalEntity100001930 yago:LanguageUnit106284225 yago:Part113809207 yago:Relation100031921 drug yago:WikicatSGLT2Inhibitors chemical substance chemical substance drug Chemical object umbel-rc:DrugProduct yago:Agent114778436 yago:Drug103247620 yago:Substance100020090 yago:Inhibitor114724436 yago:WikicatJohnson&JohnsonBrands yago:Matter100020827 yago:Name106333653 yago:TradeName106845599 yago:WikicatAnti-diabeticDrugs
label	Canagliflozin Canagliflozin Canagliflozina Canagliflozine Canagliflozin كاناجليفلوزين カナグリフロジン
comment	Canagliflozin ist ein orales Antidiabetikum zur Behandlung des Diabetes mellitus Typ 2. Es wurde von Janssen-Cilag International NV entwickelt. La canagliflozine est une molécule approuvée pour le traitement du diabète de type 2, appartenant à la famille des gliflozines. يُعد كاناجليفلوزين (بالإنجليزية: Canagliflozin)‏، الذي يُباع تحت الاسم التجاري إنفوكانا، من بين أدوية أخرى، دواء يستخدم لعلاج مرض السكري من النوع الثاني. وهو أقل تفضيلًا من الميتفورمين. يستخدم جنبا إلى جنب مع ممارسة الرياضة والنظام الغذائي. لا ينصح به عند مرض السكري من النوع الأول. يؤخذ عن طريق الفم. カナグリフロジン（Canagliflozin）は、SGLT-2阻害薬のひとつで、2型糖尿病治療薬として用いられる。製品名はカナグル（田辺三菱製薬製造販売、第一三共コ・プロモーション）。田辺三菱製薬からはテネリグリプチンとの配合剤であるカナリアも上市されている。海外ではヤンセンファーマがInvokanaという商品名で販売している。 Canagliflozin, sold under the brand name Invokana among others, is a medication used to treat type 2 diabetes. It is a third-line medication to be tried after metformin, a first-line medication for type 2 diabetes. It is used together with exercise and diet. It is not recommended in type 1 diabetes. It is taken by mouth. Canagliflozina es un medicamento comercializado con el nombre de Invokana®, y en combinación con metformina con el nombre de Vokanamet®. Fue desarrollado por y se vende bajo licencia de Janssen Pharmaceutica perteneciente al grupo Johnson & Johnson.Este fármaco pertenece al grupo de las gliflozinas cuyo mecanismo de acción está basado en la inhibición del SGLT2 ( co-transportador sodio-glucosa tipo 2) que se localiza a nivel renal y se emplea para el tratamiento de la diabetes mellitus tipo 2. Il Canagliflozin (commercializzato negli Stati Uniti d'America con il nome Invokana) è un farmaco per il trattamento del diabete mellito di tipo 2.È stato sviluppato da ed è commercializzato sotto licenza da , una divisione della Johnson & Johnson. Nel marzo del 2013, il canagliflozin è diventato il primo inibitore del SGLT2 ad essere approvato negli Stati Uniti.
sameAs	Canagliflozin Canagliflozin Canagliflozin Canagliflozin Canagliflozin Canagliflozin Canagliflozin Canagliflozin Canagliflozin Canagliflozin Canagliflozin Canagliflozin Canagliflozin Canagliflozin Canagliflozin Canagliflozin Canagliflozin
topic	dbr:Canagliflozin/metformin dbr:SGLT2_inhibitor ATC code A10 dbr:ATC_code_A10BX11 dbr:ATCvet_code_QA10BX11 Discovery and development of gliflozins Phlorizin dbr:Diabetes_medication dbr:ATC_code_A10BK02 dbr:Prominad Fournier gangrene Sodium-glucose transport proteins dbr:Daiichi_Sankyo dbr:Dr._Reddy's_Laboratories dbr:Vlado_Perkovic dbr:TA-7284 dbr:TA_7284 dbr:C24H25FO5S dbr:Renal_glucose_reabsorption dbr:Invocana dbr:Invokana dbr:JNJ-24831754 dbr:Sulisent wikipedia-en:Canagliflozin dbr:Canagliflozin#this dbr:List_of_drugs:_C–Ca
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