About: BHLHE41

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An Entity of Type : yago:Origin107323922, within Data Space : covidontheweb.inria.fr associated with source document(s)

"Basic helix-loop-helix family, member e41", or BHLHE41, is a gene that encodes a basic helix-loop-helix transcription factor repressor protein in various tissues of both humans and mice. It is also known as DEC2, hDEC2, and SHARP1, and was previously known as "basic helix-loop-helix domain containing, class B, 3", or BHLHB3. BHLHE41 is known for its role in the circadian molecular mechanisms that influence sleep quantity as well as its role in immune function and the maturation of T helper type 2 cell lineages associated with humoral immunity.

Attributes	Values
type	Thing biomolecule gene yago:Abstraction100002137 yago:Event100029378 yago:PsychologicalFeature100023100 yago:YagoPermanentlyLocatedEntity Biomolecule protein HumanGene dbo:Gene yago:Cause107326557 yago:Factor107327805 yago:WikicatTranscriptionFactors yago:Happening107283608 yago:Beginning107290905 yago:Origin107323922
label	BHLHE41 BHLHE41 DEC2
comment	BHLHE41(Basic helix-loop-helix family, member e41)은 인간과 생쥐의 다양한 조직에서 (basic helix-loop-helix) 전사인자(transcription factor,TF) 억제 단백질을 암호화하는 유전자이다. DEC2, hDEC2 및 SHARP1이라고도하며 이전에는 BHLHB3(basic helix-loop-helix domain containing, class B, 3)으로 알려져있었다. BHLHE41은 수면량에 영향을 미치는 일주기 분자 메커니즘에서의 역할뿐만 아니라 면역 기능에서의 역할 및 체액 면역과 관련된 보조 T세포(Helper T cell)의 T보조2형 세포(T helper type 2 cell ) 계통의 성숙으로 알려져있다. "Basic helix-loop-helix family, member e41", or BHLHE41, is a gene that encodes a basic helix-loop-helix transcription factor repressor protein in various tissues of both humans and mice. It is also known as DEC2, hDEC2, and SHARP1, and was previously known as "basic helix-loop-helix domain containing, class B, 3", or BHLHB3. BHLHE41 is known for its role in the circadian molecular mechanisms that influence sleep quantity as well as its role in immune function and the maturation of T helper type 2 cell lineages associated with humoral immunity. BHLHE41 (англ. Basic helix-loop-helix family member e41) – білок, який кодується однойменним геном, розташованим у людей на короткому плечі 12-ї хромосоми. Довжина поліпептидного ланцюга білка становить 482 амінокислот, а молекулярна маса — 50 498. Важливим парологом цього гена є BHLHE40. Працює як корепресор RXR. Послідовність амінокислот A: АланінC: ЦистеїнD: Аспарагінова кислотаE: Глутамінова кислотаF: ФенілаланінG: ГліцинH: ГістидинI: ІзолейцинK: ЛізинL: ЛейцинM: МетіонінN: АспарагінP: ПролінQ: ГлутамінR: АргінінS: СеринT: ТреонінV: ВалінW: Триптофан Y: Тирозин
sameAs	BHLHE41 BHLHE41 BHLHE41 BHLHE41 BHLHE41 BHLHE41 BHLHE41 BHLHE41
topic	dbr:Familial_sleep_traits dbr:SHARP1 dbr:BHLHB3 dbr:BHLHE41_(gene) dbr:DEC2 dbr:HDEC2 dbr:List_of_human_protein-coding_genes_1 Sterol regulatory element-binding protein 1 wikipedia-en:BHLHE41 dbr:BHLHE41#this dbr:Familial_natural_short_sleep
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subject	Transcription factors
dbo:wikiPageID	15416683(xsd:integer)
Wikipage revision ID	1116748305(xsd:integer)
Link from a Wikipage to another Wikipage	Adipogenesis IL-2 receptor CYP2D6 dbr:EHMT2 protein methylation asthma base pair C-terminus Chemotherapy Circadian clock Exon Gene regulatory network Glycine Memory consolidation Negative feedback Point mutation protein dimer SUMO protein Skeletal muscle T helper cell Transcription factor Epithelial–mesenchymal transition Expressed sequence tag Ovalbumin Sarcoma CLOCK PER2 Period (gene) amino acid Apoptosis

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