About: Alexandre Boissonnas   Goto Sponge  NotDistinct  Permalink

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  • Alexandre Boissonnas is an immunologist with a tenured position in the French National Institute of Medical Research (Inserm). During his PhD until 2004, he studied the role of the antigen in the homeostasis of peripheral T lymphocytes. He then joined Sebastian Amigorena‘s lab at Institut Curie-Paris to develop a new approach on the study of leukocyte dynamic using two-photon live imaging. Since 2009 he joined the Inserm at CIMI-Paris and now focus his investigations on the role of the mononuclear phagocyte system in inflammatory pathologies. Using multimodal non-linear optical imaging in mouse models, he works on the distinct roles between monocyte-derived cells and tissue-resident macrophages and tracks their respective behaviors in their physiological environment. Based on this technical innovation he aims proposing a spatio-temporal integrative schema of mononuclear phagocyte origin and function in the course of inflammatory response and during immune-mediated therapies.
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