About: activated partial thromboplastin time assay   Goto Sponge  NotDistinct  Permalink

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AttributesValues
type
label
  • activated partial thromboplastin time assay
subClassOf
described by
term editor
  • Alan Ruttenberg
  • OBI call
example of usage
  • The activated partial thromboplastin time (aPTT) was determined using Dade Actin FSL activated PTT reagent (PMID:19696660)
definition
  • An assay that evaluates blood coagulation by measuring the time required for the appearance of fibrin strands following the mixing blood or plasma with phospholipid platelet substitute (e.g., crude cephalins, soybean phosphatides). It is a test of the intrinsic pathway (factors VIII, IX, XI, and XII) and the common pathway (fibrinogen, prothrombin, factors V and X) of blood coaguation . It is used as a screening test and to monitor heparin therapy.
definition source
  • url:http://www.ebi.ac.uk/ols/ontologies/efo/terms?short_form=EFO_0004310
alternative label
  • aPTT assay
editor preferred term
  • activated partial thromboplastin time assay
has curation status
editor note
  • There is also the 'partial thromboplastin assay', which some people use synonymously to aPPT, but historically was done slightly differently (without adding a coagulant).
is topic of
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