About: Frequent detection of human rhinoviruses, paramyxoviruses, coronaviruses, and bocavirus during acute respiratory tract infections

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About: Frequent detection of human rhinoviruses, paramyxoviruses, coronaviruses, and bocavirus during acute respiratory tract infections Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Frequent detection of human rhinoviruses, paramyxoviruses, coronaviruses, and bocavirus during acute respiratory tract infections
Creator	Nissen, Michael Sloots, Theo Arden, Katherine Mackay, Ian Mcerlean, Peter
Source	Medline; PMC
abstract	Viruses are the major cause of pediatric acute respiratory tract infection (ARTI) and yet many suspected cases of infection remain uncharacterized. We employed 17 PCR assays and retrospectively screened 315 specimens selected by season from a predominantly pediatric hospital‐based population. Before the Brisbane respiratory virus research study commenced, one or more predominantly viral pathogens had been detected in 15.2% (n = 48) of all specimens. The Brisbane study made an additional 206 viral detections, resulting in the identification of a microbe in 67.0% of specimens. After our study, the majority of microbes detected were RNA viruses (89.9%). Overall, human rhinoviruses (HRVs) were the most frequently identified target (n = 140) followed by human adenoviruses (HAdVs; n = 25), human metapneumovirus (HMPV; n = 18), human bocavirus (HBoV; n = 15), human respiratory syncytial virus (HRSV; n = 12), human coronaviruses (HCoVs; n = 11), and human herpesvirus‐6 (n = 11). HRVs were the sole microbe detected in 37.8% (n = 31) of patients with suspected lower respiratory tract infection (LRTI). Genotyping of the HRV VP4/VP2 region resulted in a proposed subdivision of HRV type A into sublineages A1 and A2. Most of the genotyped HAdV strains were found to be type C. This study describes the high microbial burden imposed by HRVs, HMPV, HRSV, HCoVs, and the newly identified virus, HBoV on a predominantly paediatric hospital population with suspected acute respiratory tract infections and proposes a new formulation of viral targets for future diagnostic research studies. J. Med. Virol. 78:1232–1240, 2006. © 2006 Wiley‐Liss, Inc.
has issue date	2006-07-17(xsd:dateTime)
bibo:doi	10.1002/jmv.20689
bibo:pmid	16847968
has license	no-cc
sha1sum (hex)	ffb19069942eaecf93033b70e3a97663a2c74551
schema:url	https://doi.org/10.1002/jmv.20689
resource representing a document's title	Frequent detection of human rhinoviruses, paramyxoviruses, coronaviruses, and bocavirus during acute respiratory tract infections
has PubMed Central identifier	PMC7167201
has PubMed identifier	16847968
schema:publication	J Med Virol
resource representing a document's body	covid:ffb19069942eaecf93033b70e3a97663a2c74551#body_text
is schema:about of	named entity 'human herpesvirus-6' named entity 'retrospectively' named entity 'VP4' named entity 'high' named entity 'describes' named entity 'MAJOR' named entity 'BRISBANE' named entity 'STRAINS' named entity 'PEDIATRIC' named entity 'specimens' named entity 'RNA' named entity 'microbes' named entity 'screened' named entity 'sole' named entity 'respiratory' named entity 'human metapneumovirus' named entity 'study' named entity 'detected' named entity 'target' named entity 'human' named entity 'Brisbane' named entity 'remain' named entity 'commenced' named entity 'human coronaviruses' named entity 'detected' named entity 'Human' named entity 'microbial' named entity 'HMPV' named entity 'lower respiratory tract infection' named entity 'PCR' named entity 'HBoV' named entity 'adenoviruses' named entity 'infection' named entity 'human bocavirus' named entity 'Viruses' named entity 'Paramyxoviruses' named entity 'microbe' named entity 'HRV' named entity 'HRV' named entity 'HRV' named entity 'nosocomial infection' named entity 'HRV' named entity 'study population' named entity 'HRSV' named entity 'Parvovirus B19' named entity 'microbes' named entity 'RT-PCR' named entity 'PCR' named entity 'viruses' named entity 'Monto' named entity 'HRV' named entity 'Parvoviridae' named entity 'GenBank' named entity 'viruses' named entity 'HRV' named entity 'respiratory syncytial virus' named entity 'PCR' named entity 'HRV' named entity 'Bordetella pertussis' named entity 'HCoV-NL63' named entity 'HKU1' named entity 'HRSV' named entity 'parameter estimation' named entity 'influenza virus' named entity 'infection' named entity 'HRV' named entity 'HRV' named entity 'respiratory viral infections' named entity 'Mossman' named entity 'Australia' named entity 'influenza virus' named entity 'viral infection' named entity 'lower respiratory tract infection' named entity 'microbe' named entity 'amplicon' named entity 'pathogens' named entity 'respiratory tract infection'

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