About: Molecular Detection of Human Metapneumovirus and Human Bocavirus on Oropharyngeal Swabs Collected from Young Children with Acute Respiratory Tract Infections from Rural and Peri-Urban Communities in South India

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About: Molecular Detection of Human Metapneumovirus and Human Bocavirus on Oropharyngeal Swabs Collected from Young Children with Acute Respiratory Tract Infections from Rural and Peri-Urban Communities in South India Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Molecular Detection of Human Metapneumovirus and Human Bocavirus on Oropharyngeal Swabs Collected from Young Children with Acute Respiratory Tract Infections from Rural and Peri-Urban Communities in South India
Creator	Gopalan, • Nandagopal, Balaji Narayanan, Harikrishnan Sankar, Sathish Simoes, Eric
Source	Medline; PMC
abstract	BACKGROUND: Acute respiratory tract infections (ARTIs) are one of the major causes of morbidity and mortality among young children in developing countries. Information on the incidence of human metapneumovirus (hMPV) and human bocavirus (HBoV) infections in developing countries, especially among rural children, is very limited. OBJECTIVES: This study was conducted to identify whether these viruses were associated with ARTI among children ≤5 years of age in rural and peri-urban populations in South India. METHODS: The study was cross-sectional with prospective sample collection. Oropharyngeal swabs were collected from children ≤5 years of age presenting with ARTI. None of the children in this study were known to have any immunosuppressive conditions. The two viruses, hMPV and HBoV, were identified using semi-nested polymerase chain reaction (PCR) assays and one-step PCR assays, respectively. The lower limits of detection of hMPV and HBoV were 6.69 × 10(5) plasmid copies and 5.77 × 10(3) plasmid copies, respectively, per 5 μL PCR reaction input. RESULTS: The frequency of hMPV infection in children was higher than that of HBoV infection. The different frequencies of hMPV in patients in various age groups with upper and lower respiratory tract infections were compared, and the variance was found to be insignificant. In the 38 children who were hMPV positive, the majority (73.7 %) were from rural communities. The overall hMPV-positive rate was higher in the rural population than in the peri-urban population, but the difference was statistically insignificant. The youngest age at which hMPV-positive status was recorded was 5 months. CONCLUSION: This study demonstrated that hMPV was associated with a significant number (i.e. >10 %) of ARTIs in children in South India, whereas a relatively smaller number of HBoV infections was observed.
has issue date	2013-04-05(xsd:dateTime)
bibo:doi	10.1007/s40291-013-0030-y
bibo:pmid	23559038
has license	no-cc
sha1sum (hex)	ff4f51ae99d2ddb66894a098de0fcd416c9320bd
schema:url	https://doi.org/10.1007/s40291-013-0030-y
resource representing a document's title	Molecular Detection of Human Metapneumovirus and Human Bocavirus on Oropharyngeal Swabs Collected from Young Children with Acute Respiratory Tract Infections from Rural and Peri-Urban Communities in South India
has PubMed Central identifier	PMC7099897
has PubMed identifier	23559038
schema:publication	Mol Diagn Ther
resource representing a document's body	covid:ff4f51ae99d2ddb66894a098de0fcd416c9320bd#body_text
is schema:about of	named entity 'OROPHARYNGEAL' named entity 'RURAL' named entity 'PCR' named entity 'infection' named entity 'ARTIs' named entity 'infections' named entity 'PERI' named entity 'SOUTH' named entity 'ONE OF' named entity 'IDENTIFIED' named entity 'CONDITIONS' named entity 'INFORMATION' named entity 'STUDY' named entity 'VIRUSES' covid:arg/ff4f51ae99d2ddb66894a098de0fcd416c9320bd named entity 'USING' named entity 'THESE' named entity 'AGE' named entity 'DIFFERENT' named entity 'AGE GROUPS' named entity 'IMMUNOSUPPRESSIVE' named entity 'SOUTH' named entity 'MONTHS' named entity 'INFECTION' named entity 'OBJECTIVES' named entity 'KNOWN' named entity 'OBSERVED' named entity 'RURAL POPULATION' named entity 'LIMITS OF DETECTION' named entity 'INDIA' named entity 'PROSPECTIVE' named entity 'MORBIDITY AND MORTALITY' named entity 'OROPHARYNGEAL' named entity 'METHODS' named entity 'PLASMID' named entity 'INPUT' named entity 'HUMAN METAPNEUMOVIRUS' named entity 'YEARS' named entity 'NUMBER' named entity 'RESPIRATORY TRACT INFECTIONS' named entity 'DETECTION' named entity 'HUMAN BOCAVIRUS' named entity 'MOLECULAR' named entity 'URBAN' named entity 'YOUNG CHILDREN' named entity 'COLLECTED' named entity 'ACUTE' named entity 'URBAN' named entity 'BACKGROUND' named entity 'STEP' named entity 'DEVELOPING COUNTRIES' named entity '5B10' named entity 'CAUSES' named entity 'CONCLUSION' named entity 'COMPARED' named entity 'HUMAN BOCAVIRUS' named entity 'FOUND' named entity 'RURAL' named entity 'MAJOR' named entity 'POSITIVE' named entity 'SMALLER' named entity 'BUT' named entity 'FREQUENCIES' named entity 'COPIES' named entity 'URBAN POPULATION' named entity 'ACUTE' named entity 'SAMPLE COLLECTION' named entity 'YOUNGEST' named entity 'LOWER' named entity 'VARIOUS' named entity '28I' named entity 'OVERALL' named entity 'SIGNIFICANT' named entity 'STATUS' named entity 'COLLECTED' named entity 'CROSS-SECTIONAL' named entity 'RATE'

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