About: Exploring the pros and cons of new approaches for gamete cross-border donation based on fresh and vitrified oocytes

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Exploring the pros and cons of new approaches for gamete cross-border donation based on fresh and vitrified oocytes
Creator	Bartolucci, S Buratini, J Capuzzo, M Dal Canto, M Marca, A Mignini Renzini, M Rodriguez, A Schirinzi, F Vassena,
Source	PMC
abstract	As highlighted by European statistics, the employment of donor oocytes is a growing option for women who cannot make use of their own gametes. As the potential recipients are continuously increasing in number, a donor programme which satisfies this demand is mandatory. Improvements in cryopreservation techniques, like oocyte and embryo vitrification, have led to the overcoming of the sequence of stimulation-retrieval-transfer both from a spatial and a temporal point of view, with the development of cryobanks of oocytes permitting crossborder donation. However, while some studies report comparable success when using vitrified and fresh oocytes we still need to investigate whether the use of fresh oocytes give higher live birth rate than cryopreserved ones, when the same number of oocytes are given. The performance of embryo cryopreservation, conversely, seems to be more reliable. A novel approach based on the shipment of frozen sperm from the recipient’s country to the oocyte donor’s one, where fresh oocytes are inseminated and the resulting embryos frozen and transported back to the referring IVF centre to perform a frozen embryo transfer may be a good strategy. We believe that the use of frozen embryos from fresh oocytes could be associated with a higher cumulative live birth rate per cycle, while favouring personalised oocyte recipient care with a flexible number of oocytes assigned and limiting the burden of travelling abroad.
has issue date	2020-08-05(xsd:dateTime)
has license	cc-by
sha1sum (hex)	fe25abafa6ee17e846a49680c6292834cf845147
resource representing a document's title	Exploring the pros and cons of new approaches for gamete cross-border donation based on fresh and vitrified oocytes
has PubMed Central identifier	PMC7431201
resource representing a document's body	covid:fe25abafa6ee17e846a49680c6292834cf845147#body_text
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