About: RNA: interactions drive functionalities

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About: RNA: interactions drive functionalities Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	RNA: interactions drive functionalities
Creator	Dai, Xiaofeng Zhang, Shuo Kathia, · Rivera, Zaleta
topic	covid:fdf466b8a9174c4e3b32afc3332f1b7721f61904#this
Source	Medline; PMC
abstract	RNA is produced from the majority of human genomic sequences, although only a relatively small portion of these transcripts has known functions. Diverse RNA species interact with RNA, DNA, proteins, lipids, and metabolites to form intricate molecular networks. In this review, we attempt to delineate diverse RNA functions by interaction types between RNA and other macromolecules. Through such interactions RNAs participate in essentially every major molecular function and process, including information flow and storage, environment sensing, signal transduction, and gene regulation at transcriptional and posttranscriptional levels. Through such interactions, RNAs promote or inhibit diverse biological processes, and act as catalyzer or quencher to modulate the pace of these progresses. Alterations and personal variations of these interactions are mechanistically coupled with disease etiology and phenotypical variations for clinical use. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s11033-019-05230-7) contains supplementary material, which is available to authorized users.
has issue date	2019-12-14(xsd:dateTime)
bibo:doi	10.1007/s11033-019-05230-7
bibo:pmid	31838657
has license	no-cc
sha1sum (hex)	fdf466b8a9174c4e3b32afc3332f1b7721f61904
schema:url	https://doi.org/10.1007/s11033-019-05230-7
resource representing a document's title	RNA: interactions drive functionalities
has PubMed Central identifier	PMC7089156
has PubMed identifier	31838657
schema:publication	Mol Biol Rep
resource representing a document's body	covid:fdf466b8a9174c4e3b32afc3332f1b7721f61904#body_text
is http://vocab.deri.ie/void#inDataset of	proxy:http/ns.inria.fr/covid19/fdf466b8a9174c4e3b32afc3332f1b7721f61904
is schema:about of	named entity 'interaction' named entity 'modulate' named entity 'RNA' named entity 'DRIVE' named entity 'INTERACTIONS' named entity 'TRANSCRIPTS' named entity 'BIOLOGICAL PROCESSES' named entity 'SPECIES' named entity 'DNA' named entity 'KNOWN' named entity 'LEVELS' named entity 'SMALL' named entity 'HUMAN' named entity 'INTERACT' named entity 'FLOW' named entity 'STORAGE' named entity 'PERSONAL' named entity 'METABOLITES' named entity 'DISEASE ETIOLOGY' named entity 'PROCESS' named entity 'MAJOR' named entity 'ACT' named entity 'RNA' named entity 'DELINEATE' named entity 'ENVIRONMENT' named entity 'SENSING' named entity 'INTERACTION' named entity 'LIPIDS' named entity 'THESE' named entity 'INFORMATION' named entity 'TO FORM' named entity 'MOLECULAR FUNCTION' named entity 'TRANSCRIPTIONAL' named entity 'VARIATIONS' named entity 'PROGRESSES' named entity 'FUNCTIONS' named entity 'CLINICAL' named entity 'GENE REGULATION' named entity 'COUPLED' named entity 'NETWORKS' named entity 'FUNCTIONALITIES' named entity 'ALTERATIONS' named entity 'PACE' named entity 'MAJORITY' named entity 'MOLECULAR' named entity 'PROMOTE' named entity 'SEQUENCES' named entity 'PROTEINS' named entity 'INTERACTIONS' named entity 'TYPES' named entity 'MACROMOLECULES' named entity 'INCLUDING' named entity 'MODULATE' named entity 'PORTION' named entity 'REVIEW' named entity 'GENOMIC' named entity 'SIGNAL TRANSDUCTION' named entity 'RNA' named entity 'ATTEMPT' named entity 'DIVERSE' named entity 'USE' named entity 'POSTTRANSCRIPTIONAL' named entity 'coupled' named entity 'major' named entity 'metabolites' named entity 'majority' named entity 'flow' named entity 'RNAs' named entity 'transcriptional' named entity 'signal transduction' named entity 'posttranscriptional' named entity 'RNA' named entity 'RNAs' named entity 'miRNA' named entity 'germline cells' named entity 'protein domain'

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