About: Glycyrrhizic Acid in the Treatment of Liver Diseases: Literature Review

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Glycyrrhizic Acid in the Treatment of Liver Diseases: Literature Review
Creator	Liu, Ping Cao, Hong-Yan Cheng, Gen-Hong Li, Jian-Yuan Sun, Ming-Yu
Source	PMC
abstract	Glycyrrhizic acid (GA) is a triterpene glycoside found in the roots of licorice plants (Glycyrrhiza glabra). GA is the most important active ingredient in the licorice root, and possesses a wide range of pharmacological and biological activities. GA coupled with glycyrrhetinic acid and 18-beta-glycyrrhetic acid was developed in China or Japan as an anti-inflammatory, antiviral, and antiallergic drug for liver disease. This review summarizes the current biological activities of GA and its medical applications in liver diseases. The pharmacological actions of GA include inhibition of hepatic apoptosis and necrosis; anti-inflammatory and immune regulatory actions; antiviral effects; and antitumor effects. This paper will be a useful reference for physicians and biologists researching GA and will open the door to novel agents in drug discovery and development from Chinese herbs. With additional research, GA may be more widely used in the treatment of liver diseases or other conditions.
has issue date	2014-05-13(xsd:dateTime)
bibo:doi	10.1155/2014/872139
bibo:pmid	24963489
has license	cc-by
sha1sum (hex)	fdf03dcd427aa029a6b213288a7e862519decafb
schema:url	https://doi.org/10.1155/2014/872139
resource representing a document's title	Glycyrrhizic Acid in the Treatment of Liver Diseases: Literature Review
has PubMed Central identifier	PMC4052927
has PubMed identifier	24963489
schema:publication	Biomed Res Int
resource representing a document's body	covid:fdf03dcd427aa029a6b213288a7e862519decafb#body_text
is schema:about of	named entity 'IMMUNE' named entity 'EFFECTS' named entity 'INHIBITION' named entity 'LICORICE' named entity 'MAY BE' named entity 'ANTIVIRAL' named entity 'CONDITIONS' named entity 'CHINESE HERBS' named entity 'PAPER' named entity 'INCLUDE' named entity 'ADDITIONAL' named entity 'USED' named entity 'POSSESSES' named entity 'CHINA' named entity 'LICORICE ROOT' named entity 'RESEARCHING' named entity 'DRUG FOR LIVER DISEASE' named entity 'TRITERPENE GLYCOSIDE' named entity 'BIOLOGICAL' named entity 'ACTIVE INGREDIENT' named entity 'CURRENT' named entity 'ANTI-INFLAMMATORY' named entity 'REGULATORY' named entity 'APOPTOSIS AND NECROSIS' named entity 'ITS' named entity 'PHYSICIANS' named entity 'WIDE' named entity 'APPLICATIONS' named entity 'OF LIVER DISEASES' named entity 'JAPAN' named entity 'LIVER DISEASES' named entity 'NOVEL' named entity 'DOOR' named entity 'GLYCYRRHIZIC ACID' named entity 'MEDICAL' named entity 'TREATMENT' named entity 'OPEN' named entity 'IMPORTANT' named entity 'RESEARCH' named entity 'COUPLED' named entity 'ANTIALLERGIC DRUG' named entity 'DRUG DISCOVERY AND DEVELOPMENT' named entity 'ACTIVITIES' named entity 'IS A' named entity 'USEFUL' named entity 'REFERENCE' named entity 'GLYCYRRHIZIC ACID' named entity 'LITERATURE REVIEW' named entity 'TREATMENT' named entity 'ACTIONS' named entity 'RANGE' named entity 'REVIEW' named entity 'PHARMACOLOGICAL' named entity 'HEPATIC' named entity 'ANTITUMOR' named entity 'GLYCYRRHETINIC ACID' named entity 'FOUND' named entity 'ROOTS' named entity 'PLANTS' named entity 'BIOLOGISTS' named entity 'active ingredient' named entity 'Glycyrrhiza glabra' named entity 'pharmacological' named entity 'apoptosis' named entity 'glycyrrhetinic acid' named entity 'Chinese herbs' named entity 'Glycyrrhizic acid' named entity 'liver diseases' named entity 'liver disease' named entity 'antiviral' named entity 'hepatic' named entity 'China' named entity 'capsules' named entity 'Magnesium' named entity 'Glycyrrhizic acid' named entity 'inflammation' named entity 'Gr-1'

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