About: The relevance of respiratory viral infections in the exacerbations of chronic obstructive pulmonary disease

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About: The relevance of respiratory viral infections in the exacerbations of chronic obstructive pulmonary disease—A systematic review Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	The relevance of respiratory viral infections in the exacerbations of chronic obstructive pulmonary disease—A systematic review
Creator	Rohde, G Mallia, P Van Winden, M Zwaans, W
Source	Elsevier; Medline; PMC
abstract	BACKGROUND: Despite the increasing knowledge on the role of viruses in exacerbations of COPD (AECOPD), it is less clear which viruses are involved and to what extent they contribute to exacerbations. This review aims to systematically combine and evaluate the available literature of the prevalence of respiratory viruses in patients with AECOPD, detected by PCR. METHODS: An electronic search strategy was performed on PubMed and Embase and reference lists were screened for eligible studies. Cross-sectional, prospective studies and case-control studies were included. The primary outcome measure was the prevalence of respiratory viruses (adenovirus, bocavirus, coronavirus, EBV, hMPV, influenza, parainfluenza, rhino-/enterovirus, RSV) in respiratory secretions of patients during an AECOPD. Secondary outcomes were the odds of the presence of the viruses in different respiratory secretions and the odds of the presence of viruses in upper and lower respiratory tract (URT/LRT) samples. RESULTS: Nineteen studies with 1728 patients were included. Rhino-/enteroviruses (16.39%), RSV (9.90%) and influenza (7.83%) were the most prevalent viruses detected with lower detection rates of coronaviruses (4.08%) and parainfluenza (3.35%). Adenovirus (2.07%), hMPV (2.78%) and bocaviruses (0.56%) appear to be rare causative agents of AECOPD. Definitive conclusions regarding the role of EBV cannot be made. Seven of the eight analyzed viruses had a higher prevalence in LRT samples. Coronaviruses were detected more frequently in the URT. CONCLUSIONS: Respiratory viruses are frequently detected in both URT and LRT samples in AECOPD with rhino-/enteroviruses, RSV and influenza viruses the most prevalent viruses. Detection rates vary between the two sites for different viruses.
has issue date	2014-07-04(xsd:dateTime)
bibo:doi	10.1016/j.jcv.2014.06.025
bibo:pmid	25066886
has license	no-cc
sha1sum (hex)	fda3a341c26f401e071e365f7649e53501f4e825
schema:url	https://doi.org/10.1016/j.jcv.2014.06.025
resource representing a document's title	The relevance of respiratory viral infections in the exacerbations of chronic obstructive pulmonary disease—A systematic review
has PubMed Central identifier	PMC7106508
has PubMed identifier	25066886
schema:publication	J Clin Virol
resource representing a document's body	covid:fda3a341c26f401e071e365f7649e53501f4e825#body_text
is schema:about of	named entity 'samples' named entity 'prevalence' named entity 'viruses' named entity 'respiratory' named entity 'SYSTEMATIC REVIEW' named entity 'PCR' named entity 'INCLUDED' named entity 'CLEAR' named entity 'COPD' named entity 'KNOWLEDGE' named entity 'PARAINFLUENZA' named entity 'HMPV' named entity 'PRESENCE OF' named entity 'CROSS-SECTIONAL' named entity 'EXTENT' named entity 'STUDIES' named entity 'DETECTED' named entity 'SEARCH' named entity 'REFERENCE' named entity 'AIMS' named entity 'VIRAL INFECTIONS' named entity 'RELEVANCE' covid:arg/fda3a341c26f401e071e365f7649e53501f4e825 named entity 'PROSPECTIVE STUDIES' named entity 'OUTCOMES' named entity 'CONTRIBUTE ' named entity 'INFLUENZA' named entity 'CHRONIC OBSTRUCTIVE PULMONARY DISEASE' named entity 'RESPIRATORY' named entity 'RSV' named entity 'ODDS' named entity 'METHODS' named entity 'PERFORMED' named entity 'EVALUATE' named entity 'SAMPLES' named entity 'PUBMED' named entity 'STRATEGY' named entity 'CORONAVIRUS' named entity 'ELIGIBLE' named entity 'PREVALENCE' named entity 'AVAILABLE' named entity 'RESPIRATORY VIRUSES' named entity 'SECRETIONS' named entity 'RESPIRATORY' named entity 'VIRUSES' named entity 'BACKGROUND' named entity 'INCREASING' named entity 'BOCAVIRUS' named entity 'ROLE' named entity 'REVIEW' named entity 'SECONDARY' named entity 'COMBINE' named entity 'PATIENTS' named entity 'LOWER RESPIRATORY TRACT' named entity 'PRIMARY OUTCOME MEASURE' named entity 'CASE-CONTROL STUDIES' named entity 'ELECTRONIC' named entity 'INVOLVED' named entity 'WHAT' named entity 'EMBASE' named entity 'UPPER' named entity 'EBV' named entity 'DIFFERENT' named entity 'LITERATURE' named entity 'RHINO-' named entity 'enterovirus' named entity 'detected' named entity 'respiratory tract' named entity 'PCR' named entity 'Methods' named entity 'electronic search' named entity 'lower respiratory tract' named entity 'adenovirus' named entity 'RSV' named entity 'EBV' named entity 'viruses' named entity 'viruses' named entity 'LRT'

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