About: Immunogenic properties of Landrace pigs selected for resistance to mycoplasma pneumonia of swine

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About: Immunogenic properties of Landrace pigs selected for resistance to mycoplasma pneumonia of swine Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Immunogenic properties of Landrace pigs selected for resistance to mycoplasma pneumonia of swine
Creator	Kitazawa, Haruki Aso, Hisashi Shimazu, Tomoyuki Suda, Yoshihito Watanabe, Kouichi Borjigin, Liushiqi Katayama, Yuki Katoh, Kazuo Li, Meihua Nakajo, Mituru Roh, Sang-Gun Sakuma, Akiko Satoh, Takumi Suzuki, Keiichi Uchida, Takafumi
Source	Medline; PMC
abstract	Mycoplasma pneumonia of swine (MPS) lung lesions and immunogenic properties were compared between a Landrace line that was genetically selected for reduced incidence of pulmonary MPS lesions, and a non‐selected Landrace line. The MPS‐selected Landrace line showed significantly lower degrees of pulmonary MPS lesions compared with the non‐selected Landrace line. When changes in immunity before and after vaccination were compared, the percentage of B cells in the peripheral blood of the MPS‐selected Landrace line was significantly lower than that of the non‐selected line. Furthermore, the concentration of growth hormone and the mitogen activity of peripheral blood mononuclear cells in the MPS‐selected Landrace line showed significantly (P < 0.05) lower increases after vaccination than the non‐selected line. Conversely, the concentration of peripheral blood interferon (IFN)‐γ and salivary immunoglobulin A (IgA) after Mycoplasma hyopneumoniae vaccination was significantly higher in the MPS‐selected Landrace line than in the non‐selected line. Gene expression of toll‐like receptor (TLR)2 and TLR4 was significantly higher in the MPS‐selected Landrace line in immune tissues, with the exception of the hilar lymph nodes. The present results suggest that peripheral blood IFN‐γ, salivary IgA TLR2, and TLR4 are important immunological factors influencing the development of MPS lesions.
has issue date	2015-08-11(xsd:dateTime)
bibo:doi	10.1111/asj.12440
bibo:pmid	26260893
has license	no-cc
sha1sum (hex)	fd87b3324f0b8f38d1e4cc08b40855cd93296d0d
schema:url	https://doi.org/10.1111/asj.12440
resource representing a document's title	Immunogenic properties of Landrace pigs selected for resistance to mycoplasma pneumonia of swine
has PubMed Central identifier	PMC7159536
has PubMed identifier	26260893
schema:publication	Anim Sci J
resource representing a document's body	covid:fd87b3324f0b8f38d1e4cc08b40855cd93296d0d#body_text
is schema:about of	named entity 'salivary' named entity 'Landrace' named entity 'interferon' named entity 'higher' named entity 'lesions' named entity 'vaccination' named entity 'lung' named entity 'swine' named entity 'MITOGEN' named entity 'LANDRACE' named entity 'TLR4' named entity 'IMMUNOLOGICAL' named entity 'EXCEPTION' named entity 'IFN' named entity 'IMMUNOGENIC' covid:arg/fd87b3324f0b8f38d1e4cc08b40855cd93296d0d named entity 'TLR4' named entity 'growth hormone' named entity 'influencing' named entity 'factors' named entity 'vaccination' named entity 'IgA' named entity 'lesions' named entity 'MPS' named entity 'Landrace' named entity 'interferon (IFN)-γ' named entity 'Landrace' named entity 'immunogenic' named entity 'hilar' named entity 'TLR4' named entity 'Mycoplasma hyopneumoniae' named entity 'immunoglobulin' named entity 'peripheral blood' named entity 'Mycoplasma pneumonia' named entity 'TLR4' named entity 'MPS' named entity 'immunogenic' named entity 'MPS' named entity 'Blood samples' named entity 'GE Healthcare' named entity 'white blood cells' named entity 'pig' named entity 'flow cytometry' named entity 'mycoplasma' named entity 'IL-13' named entity 'formalin' named entity 'immune tissues' named entity 'MPS' named entity 'RNA' named entity 'M. hyopneumoniae' named entity 'pathogens' named entity 'PAMs' named entity 'MPS' named entity 'Landrace' named entity 'Landrace' named entity 'TLR4' named entity 'Landrace' named entity 'FlowJo' named entity 'Reagent' named entity 'MLNs' named entity 'antigen' named entity 'Cary, NC' named entity 'excrement' named entity 'gel-filtration chromatography' named entity 'flow cytometry' named entity 'macrophages' named entity 'IFN-γ'

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