About: Evaluation of the protection conferred by commercial vaccines and attenuated heterologous isolates in China against the CK/CH/LDL/97I strain of infectious bronchitis coronavirus

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About: Evaluation of the protection conferred by commercial vaccines and attenuated heterologous isolates in China against the CK/CH/LDL/97I strain of infectious bronchitis coronavirus Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Evaluation of the protection conferred by commercial vaccines and attenuated heterologous isolates in China against the CK/CH/LDL/97I strain of infectious bronchitis coronavirus
Creator	Han, Zongxi Kong, Xiangang Liu, Shengwang Li, Chengren Liu, Qiaoran Tong, Guangzhi Wang, Yu Zhang, Qinxia Zhang, Xiaonan
source	Elsevier; Medline; PMC
abstract	Avian infectious bronchitis virus (IBV) causes tremendous economic losses to the poultry industry worldwide. Different serotypes of this virus show little cross-protection. The present study investigated the genotypic relationship between CK/CH/LDL/97I-type strains and reference IBVs based on S1 gene comparisons and the protection provided by vaccination with commercial vaccines and attenuated homologous and heterologous strains. Phylogenetic analysis and the comparison of S1 showed that CK/CH/LDL/97I-type virus might be a new serotype compared to vaccine strains and other types of IBV isolates in China. Protection efficacy was evaluated by morbidity, mortality, and virus re-isolation from the challenged chicks. Complete protection by IBV vaccination was provided by the homologous strain but sufficient respiratory protection was not provided by the commercial vaccines. Heterologous strains against CK/CH/LDL/97I challenge and the development of a vaccine against CK/CH/LDL/97I-type IBV will be necessary to control infectious bronchitis disease in poultry. Further development of the attenuated CK/CH/LDL/97I strain may provide a valuable contribution towards this goal.
has issue date	2007-11-01(xsd:dateTime)
bibo:doi	10.1016/j.tvjl.2007.08.018
bibo:pmid	17936045
has license	no-cc
sha1sum (hex)	fd327f9faf6b47f5efd8e3b8790018f654114878
schema:url	https://doi.org/10.1016/j.tvjl.2007.08.018
resource representing a document's title	Evaluation of the protection conferred by commercial vaccines and attenuated heterologous isolates in China against the CK/CH/LDL/97I strain of infectious bronchitis coronavirus
has PubMed Central identifier	PMC7110898
has PubMed identifier	17936045
schema:publication	Vet J
resource representing a document's body	covid:fd327f9faf6b47f5efd8e3b8790018f654114878#body_text
is schema:about of	named entity 'vaccines' named entity 'economic' named entity 'disease' named entity 'efficacy' named entity 'heterologous' named entity 'provide' named entity 'LDL' named entity 'strains' named entity 'Journal' named entity 'STRAIN' named entity 'DIFFERENT' named entity 'STRAINS' named entity 'CONTRIBUTION' named entity 'MORBIDITY' named entity 'PROVIDE' named entity 'SUFFICIENT' named entity 'PROTECTION' named entity 'DISEASE' named entity 'WORLDWIDE' named entity 'PROVIDED' named entity 'CROSS' named entity 'PROTECTION EFFICACY' named entity 'MORTALITY' named entity 'NECESSARY' named entity 'CHINA' named entity 'VETERINARY' named entity 'JOURNAL' named entity 'CHALLENGE' named entity 'COMPARISON' named entity 'STUDY' named entity 'REFERENCE' named entity 'EVALUATED' named entity 'VACCINE' named entity 'VACCINES' named entity 'ATTENUATED' named entity 'VACCINATION' named entity 'INFECTIOUS BRONCHITIS' named entity 'TO CONTROL' named entity 'HOMOLOGOUS' named entity 'BASED' named entity 'GOAL' named entity 'POULTRY' named entity 'DEVELOPMENT' named entity 'RELATIONSHIP' named entity 'INVESTIGATED' named entity 'ISOLATES' named entity 'PHYLOGENETIC ANALYSIS' named entity 'GENOTYPIC' named entity 'TYPE VIRUS' named entity 'BUT' named entity 'HETEROLOGOUS' named entity 'MIGHT BE' named entity 'PRESENT' named entity 'SEROTYPE' named entity 'TYPE' named entity 'ECONOMIC' named entity 'ISOLATION' named entity 'S1 GENE' named entity 'POULTRY INDUSTRY' named entity 'COMMERCIAL' named entity 'CHICKS' named entity 'CAUSES' named entity 'NOT PROVIDED' named entity 'SEROTYPES' named entity 'NEW' named entity 'LITTLE' named entity 'COMPLETE' named entity 'TYPES' named entity 'VIRUS' named entity 'AVIAN INFECTIOUS BRONCHITIS VIRUS' named entity 'RESPIRATORY PROTECTION' covid:arg/fd327f9faf6b47f5efd8e3b8790018f654114878 named entity 'infectious bronchitis'

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