About: The management of adult appendicitis during the COVID-19 pandemic: an interim analysis of a UK cohort study

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About: The management of adult appendicitis during the COVID-19 pandemic: an interim analysis of a UK cohort study Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	The management of adult appendicitis during the COVID-19 pandemic: an interim analysis of a UK cohort study
Creator	Lund, · Adiamah, · Boyd-Carson, · Clifford, · Cornish, · Dickerson, · Doleman, · Hare, · Hollyman, · Javanmard-Emamghissi, H Lockwood, · Moug, · Pearce, · Richards, · Tierney, ·
Source	Medline; PMC
abstract	BACKGROUND: Acute appendicitis (AA) is the most common general surgical emergency. Early laparoscopic appendicectomy is the gold-standard management. SARS-CoV-2 (COVID-19) brought concerns of increased perioperative mortality and spread of infection during aerosol generating procedures: as a consequence, conservative management was advised, and open appendicectomy recommended when surgery was unavoidable. This study describes the impact of the first weeks of the pandemic on the management of AA in the United Kingdom (UK). METHODS: Patients 18 years or older, diagnosed clinically and/or radiologically with AA were eligible for inclusion in this prospective, multicentre cohort study. Data was collected from 23rd March 2020 (beginning of the UK Government lockdown) to 1st May 2020 and included: patient demographics, COVID status; initial management (operative and conservative); length of stay; and 30-day complications. Analysis was performed on the first 500 cases with 30-day follow-up. RESULTS: The patient cohort consisted of 500 patients from 48 sites. The median age of this cohort was 35 [26–49.75] years and 233 (47%) of patients were female. Two hundred and seventy-one (54%) patients were initially treated conservatively; with only 26 (10%) cases progressing to an operation. Operative interventions were performed laparoscopically in 44% (93/211). Median length of hospital stay was significantly reduced in the conservatively managed group (2 [IQR 1–4] days vs. 3 [2–4], p < 0.001). At 30 days, complications were significantly higher in the operative group (p < 0.001), with no deaths in any group. Of the 159 (32%) patients tested for COVID-19 on admission, only 6 (4%) were positive. CONCLUSION: COVID-19 has changed the management of acute appendicitis in the UK, with non-operative management shown to be safe and effective in the short-term. Antibiotics should be considered as the first line during the pandemic and perhaps beyond.
has issue date	2020-07-15(xsd:dateTime)
bibo:doi	10.1007/s10151-020-02297-4
bibo:pmid	32671661
has license	cc-by
sha1sum (hex)	fc370f754862b736882b09d039d5433179fad390
schema:url	https://doi.org/10.1007/s10151-020-02297-4
resource representing a document's title	The management of adult appendicitis during the COVID-19 pandemic: an interim analysis of a UK cohort study
has PubMed Central identifier	PMC7362319
has PubMed identifier	32671661
schema:publication	Tech Coloproctol
resource representing a document's body	covid:fc370f754862b736882b09d039d5433179fad390#body_text
is schema:about of	named entity 'perioperative mortality' named entity 'management' named entity 'UK Government' named entity 'inclusion' named entity 'PANDEMIC' named entity 'PROSPECTIVE' named entity 'CASES' named entity 'complications' named entity 'collected' named entity 'length' named entity 'Acute appendicitis' named entity 'Patients' named entity 'Data' named entity 'open' named entity 'Acute appendicitis' named entity 'United Kingdom' named entity 'diagnosed clinically' named entity 'COVID' named entity 'perioperative mortality' named entity 'appendicectomy' named entity 'interim analysis' named entity 'Laparoscopic' named entity 'principal investigator' named entity 'perforation' named entity 'appendicectomy' named entity 'Europe' named entity 'open procedure' named entity 'statistical analysis' named entity 'interquartile range' named entity 'appendicitis' named entity 'emergency care' named entity 'acute appendicitis' named entity 'CT imaging' named entity 'surgical site infections' named entity 'professional association' named entity 'antibiotics' named entity 'ultrasound' named entity 'COVID-19 pandemic' named entity 'SPSS' named entity 'mortality rate' named entity 'observational studies' named entity 'acute appendicitis' named entity 'Laparoscopic' named entity 'Laparoscopic' named entity 'COVID-19 pandemic' named entity 'observational study' named entity 'secondary care' named entity 'critical care' named entity 'IBM' named entity 'laparoscopic surgery' named entity 'abscess' named entity 'surgical management' named entity 'STROBE' named entity 'appendix removed' named entity 'Epidemiology' named entity 'hemicolectomy' named entity 'COVID' named entity 'open surgery' named entity 'critical care' named entity 'FFP3' named entity 'clinical care' named entity 'CT scan' named entity 'open procedures' named entity 'infection' named entity 'abscess' named entity 'Laparoscopic' named entity 'comorbidities'

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