About: Changes in the coagulation-fibrinolysis balance of endothelial cells and mononuclear phagocytes: role in disseminated intravascular coagulation associated with infectious diseases

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About: Changes in the coagulation-fibrinolysis balance of endothelial cells and mononuclear phagocytes: role in disseminated intravascular coagulation associated with infectious diseases Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Changes in the coagulation-fibrinolysis balance of endothelial cells and mononuclear phagocytes: role in disseminated intravascular coagulation associated with infectious diseases
Creator	Colucci, Mario Semeraro, Nicola
Source	PMC
abstract	Over the last few years, evidence has accumulated that the pathogenetic mechanism of disseminated intravascular coagulation encountered in patients with infectious diseases is extraordinarily complex and involves multiple interactions between the microorganism itself and/or a number of mediators, both microorganism derived and host manufactured, and multifunctional cellular systems, namely endothelial cells and mononuclear phagocytes. In particular, infectious agents and mediators shift the coagulation-fibrinolysis equilibrium of these cells towards fibrin formation and accumalation, via enhancement of procoagulant and fibrinolytic capacities. New insights into the pathogenetic mechanism may have important implications for the management of infected patients with disseminated intravascular coagulation.
has issue date	1992-01-01(xsd:dateTime)
bibo:doi	10.1007/bf02591649
bibo:pmid	1591371
has license	no-cc
sha1sum (hex)	fc25f4ae0e57e01e615af31395ed34b99f62b93a
schema:url	https://doi.org/10.1007/bf02591649
resource representing a document's title	Changes in the coagulation-fibrinolysis balance of endothelial cells and mononuclear phagocytes: role in disseminated intravascular coagulation associated with infectious diseases
has PubMed Central identifier	PMC7102176
has PubMed identifier	1591371
schema:publication	Int J Clin Lab Res
resource representing a document's body	covid:fc25f4ae0e57e01e615af31395ed34b99f62b93a#body_text
is schema:about of	named entity 'enhancement' named entity 'MANAGEMENT' named entity 'ANTICOAGULANT' named entity 'FIBRIN' named entity 'EVIDENCE' named entity 'ACCUMULATION' named entity 'INTERACTIONS' named entity 'INFECTED' named entity 'MAY HAVE' named entity 'equilibrium' named entity 'phagocytes' named entity 'disseminated intravascular coagulation' named entity 'microorganism' named entity 'anticoagulant' named entity 'disseminated intravascular coagulation' named entity 'pathogenetic' named entity 'fibrinolysis' named entity 'coagulation' named entity 'disseminated intravascular coagulation' named entity 'clotting factors' named entity 'procoagulant' named entity 'dramatic increase' named entity 'plasma levels' named entity 'viral infections' named entity 'mononuclear phagocytes' named entity 'factor IX' named entity 'fibrinolytic' named entity 'DIC' named entity 'mRNA degradation' named entity 'continuous infusion' named entity 'PAI-1' named entity 'DIC' named entity 'plasma' named entity 'endotoxin' named entity 'prothrombin' named entity 'plasmin' named entity 'fibrinolysis' named entity 'non-thrombogenic' named entity 'gene' named entity 'cellular tissue' named entity 'mononuclear phagocytes' named entity 'endothelial cells' named entity 'recombinant' named entity 'endothelial' named entity 'smooth muscle cells' named entity 'blood coagulation' named entity 'plasma levels' named entity 'secretion' named entity 'microcirculation' named entity 'thrombomodulin' named entity 'factor VII' named entity 'fibrin' named entity 'cyto' named entity 'naturally occurring' named entity 'tissue factor' named entity 'endogenous' named entity 'mononuclear phagocytes' named entity 'interleukin-1' named entity 'thrombus' named entity 'experimental evidence' named entity 'clotting factors' named entity 'microorganisms' named entity 'coagulation' named entity 'procoagulant' named entity 'intravascular coagulation' named entity 'thrombocytopenia' named entity 'spleen' named entity 'hemostatic' named entity 'thrombotic' named entity 'thrombin' named entity 'plasminogen activator' named entity 'infusion' named entity 'phase 1 trial' named entity 'mononuclear cells' named entity 'pathological process' named entity 'pathogenetic' named entity 'cell wall components' named entity 'anatomical' named entity 'blood clotting' named entity 'endotoxin'

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