About: Coronavirus infection of the central nervous system: host

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About: Coronavirus infection of the central nervous system: host–virus stand-off Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Coronavirus infection of the central nervous system: host–virus stand-off
Creator	Bergmann, Cornelia Lane, Thomas Stohlman, Stephen
source	Medline; PMC
abstract	Several viruses infect the mammalian central nervous system (CNS), some with devastating consequences, others resulting in chronic or persistent infections associated with little or no overt pathology. Coronavirus infection of the murine CNS illustrates the contributions of both the innate immune response and specific host effector mechanisms that control virus replication in distinct CNS cell types. Despite T-cell-mediated control of acute virus infection, host regulatory mechanisms, probably designed to protect CNS integrity, contribute to the failure to eliminate virus. Distinct from cytolytic effector mechanisms expressed during acute infection, non-lytic humoral immunity prevails in suppressing infectious virus during persistence.
has issue date	2006-01-01(xsd:dateTime)
bibo:doi	10.1038/nrmicro1343
bibo:pmid	16415928
has license	no-cc
sha1sum (hex)	fbc4bdeb71a7c17e45d1de5f016b9b994052f085
schema:url	https://doi.org/10.1038/nrmicro1343
resource representing a document's title	Coronavirus infection of the central nervous system: host–virus stand-off
has PubMed Central identifier	PMC7096820
has PubMed identifier	16415928
schema:publication	Nat Rev Microbiol
resource representing a document's body	covid:fbc4bdeb71a7c17e45d1de5f016b9b994052f085#body_text
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