About: Study protocol for a double-blind, randomised placebo-controlled trial evaluating clinical effects of platelet-rich plasma injection for acute grade-2 hamstring tear among high performance athletes

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Study protocol for a double-blind, randomised placebo-controlled trial evaluating clinical effects of platelet-rich plasma injection for acute grade-2 hamstring tear among high performance athletes Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Study protocol for a double-blind, randomised placebo-controlled trial evaluating clinical effects of platelet-rich plasma injection for acute grade-2 hamstring tear among high performance athletes
Creator	Munawwar, Ahmad Salim, Helmi
Source	PMC
abstract	INTRODUCTION: Hamstring injury among athletes often results in significant morbidity. Currently, there are controversies regarding the clinical use of platelet-rich plasma (PRP) for the treatment of acute hamstring injury. METHODS AND ANALYSIS: This study is a single-centre double-blind randomised placebo-controlled trial. Sixty-eight patients will be randomised to receive under ultrasound guidance either a single injection of leucocyte-rich PRP (LR-PRP) or normal saline. All patients will undergo a standardised hamstring rehabilitation programme under the supervision of a sports physiotherapist. Outcome data will be collected before intervention (baseline), and thereafter on a weekly basis. The primary outcome measure is the duration to return-to-play. It is defined as the duration (in days) from the date on which the injury occurred until the patients were pain-free, able to perform the active knee extension test and have regained hamstring muscle strength. Secondary outcome measures include assessment of pain intensity and the effect of pain on to day-to-day functions using the self-reported Brief Pain Inventory—Short Form questionnaire. Both the primary and secondary outcomes were assessed at baseline and thereafter once a week until return to play. Also, hamstring injury recurrence within the first 6 months after recovery will be monitored via telephone. The results of this study will provide insights into the effect of LR-PRP in muscle and may help to identify the best PRP application protocol for muscle injuries. ETHICS AND DISSEMINATION: Ethics approval were obtained from the Medical Research Ethics Committee of the University of Malaya Medical Centre. Results of this trial will be submitted for publication in a peer-reviewed journal. TRIAL REGISTRATION NUMBER: ISRCTN76844299.
has issue date	2020-08-20(xsd:dateTime)
bibo:doi	10.1136/bmjopen-2020-039105
bibo:pmid	32820000
has license	cc-by-nc
sha1sum (hex)	fb42e1addd2c640a3767172ecd883d6e4248fb42
schema:url	https://doi.org/10.1136/bmjopen-2020-039105
resource representing a document's title	Study protocol for a double-blind, randomised placebo-controlled trial evaluating clinical effects of platelet-rich plasma injection for acute grade-2 hamstring tear among high performance athletes
has PubMed Central identifier	PMC7443311
has PubMed identifier	32820000
schema:publication	BMJ Open
resource representing a document's body	covid:fb42e1addd2c640a3767172ecd883d6e4248fb42#body_text
is schema:about of	named entity 'trial' named entity 'tear' named entity 'hamstring' named entity 'grade-2' named entity 'platelet-rich plasma' named entity 'normal saline' named entity 'red blood cell' named entity 'Multiple imputation' named entity 'intention-to-treat' named entity 'ultrasound' named entity 'ultrasound' named entity 'radiological imaging' named entity 'ultrasound' named entity 'PRP' named entity 'randomisation' named entity 'clinical trials' named entity 'normal saline' named entity 'PRP' named entity 'muscle' named entity 'diagnostic ultrasound' named entity 'muscle' named entity 'ultrasound' named entity 'venous blood' named entity 'anticoagulant' named entity 'National Sport' named entity 'local anaesthetic' named entity 'study protocol' named entity 'Trial registration' named entity 'Sysmex' named entity 'Warsaw' named entity 'normal saline' named entity 'PRP' named entity 'adverse effects' named entity 'Rest, ice, compression and elevation' named entity 'muscle' named entity 'muscle injury' named entity 'Citrate' named entity 'non-steroidal anti-inflammatories' named entity 'venous blood' named entity 'PRP' named entity 'ITT' named entity 'intention-to-treat' named entity 'diagnostic ultrasound' named entity 'area 18' named entity 'Mann-Whitney U test' named entity 'ischial tuberosity' named entity 'PRP' named entity 'Social Sciences' named entity 'GPS' named entity 'PRP' named entity 'Australian rules football' named entity 'outcome variable' named entity 'significant difference' named entity 'aseptic technique' named entity 'physical examination' named entity 'PRP' named entity 'study protocol' named entity 'GPS' named entity 'sodium bicarbonate' named entity 'growth factors' named entity 'Biomet' named entity 'MCO' named entity 'randomisation' named entity 'ultrasound' named entity 'PRP' named entity 'clinical trials register' named entity 'informed consent' named entity 'application protocol' named entity 'clinical trials register' named entity 'aseptic technique' named entity 'transforming growth factor-β1' named entity 'PRP' named entity 'physiotherapists' named entity 'PRP' named entity 'clinical practice' named entity 'growth factors' named entity 'muscle' named entity 'design of the study' named entity 'missing data' named entity 'clinical laboratory'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software