About: Hypernatremia—A Manifestation of COVID-19: A Case Series

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Hypernatremia—A Manifestation of COVID-19: A Case Series
Creator	Michelsen, Andrea Mols, Georg Priebe, Hans-Joachim Vogt, Ulrike Weißer, Christian Zimmer, Milena Zink, Anne
Source	PMC
abstract	We report for the first time therapy-resistant hypernatremia (plasma sodium concentration ≥150 mmol per liter) developing in 6 of 12 critically ill coronavirus disease 2019 (COVID-19) patients age 57–84 years requiring mechanical ventilation. There was no correlation between plasma sodium concentrations and sodium input. Plasma concentrations of chloride were elevated, those of potassium decreased. These findings are consistent with abnormally increased renal sodium reabsorption, possibly caused by increased angiotensin II activity secondary to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)–induced downregulation of angiotensin-converting enzyme 2 (ACE2) receptors. As hypernatremia was associated with increased length of intensive care unit stay, special attention should be paid to the electrolyte status of COVID-19 patients.
has issue date	2020-07-24(xsd:dateTime)
bibo:doi	10.1213/xaa.0000000000001295
has license	no-cc
sha1sum (hex)	faeada1db5c53d0d20ed6d8aa4e99252235ee6bc
schema:url	https://doi.org/10.1213/xaa.0000000000001295
resource representing a document's title	Hypernatremia—A Manifestation of COVID-19: A Case Series
has PubMed Central identifier	PMC7409524
schema:publication	A A Pract
resource representing a document's body	covid:faeada1db5c53d0d20ed6d8aa4e99252235ee6bc#body_text
is schema:about of	named entity 'stay' named entity 'liter' named entity 'COVID-19' named entity 'REPORT' named entity 'ACTIVITY' named entity 'DOWNREGULATION' named entity 'INCREASED' named entity 'downregulation' named entity 'COVID-19' named entity 'Practice' named entity 'length' named entity 'plasma' named entity 'potassium' named entity 'downregulation' named entity 'COVID' named entity 'intensive care unit' named entity 'sodium' named entity 'sodium' named entity 'chloride' named entity 'ACE2' named entity 'mechanical ventilation' named entity 'COVID-19' named entity 'Case Series' named entity 'consistent' named entity 'elevated' named entity 'weaning' named entity 'COVID-19' named entity 'hypernatremia' named entity 'hypernatremia' named entity 'ACE2' named entity 'intravenous administration' named entity 'sodium' named entity 'plasma' named entity 'analgesia' named entity 'reference range' named entity 'Plasma' named entity 'renal chloride reabsorption' named entity 'sodium' named entity 'hypernatremia' named entity 'SARS-CoV-2' named entity 'COVID-19' named entity 'protein' named entity 'Proteinuria' named entity 'hypokalemia' named entity 'ICU' named entity 'infection' named entity 'hypernatremia' named entity 'receptor' named entity 'dialysis' named entity 'proximal convoluted tubule' named entity 'sodium' named entity 'hypernatremia' named entity 'Radiometer' named entity 'laboratory testing' named entity 'Copenhagen' named entity 'ACE2 receptor' named entity 'Angiotensin II' named entity 'hypernatremia' named entity 'RNA' named entity 'EQUATOR' named entity 'renal sodium reabsorption' named entity 'body mass index' named entity 'diuretics' named entity 'reference range' named entity 'Perspiration' named entity 'mechanical ventilation' named entity 'creatinine' named entity 'COVID' named entity 'sodium' named entity 'renal tubular' named entity 'hypernatremia' named entity 'sodium' named entity 'mmol' named entity 'Siemens Healthcare' named entity 'hypokalemia' named entity 'mmol' named entity 'Hypernatremia'

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