About: Comparative metabolomic analysis of Sinorhizobium sp. C4 during the degradation of phenanthrene

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About: Comparative metabolomic analysis of Sinorhizobium sp. C4 during the degradation of phenanthrene Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Comparative metabolomic analysis of Sinorhizobium sp. C4 during the degradation of phenanthrene
Creator	Li, Qing Kim, Han Jeong, & Keum, Young Su, Jong
Source	PMC
abstract	Comparative metabolic responses of Sinorhizobium sp. C4 were investigated. Comprehensive metabolites profiles, including polar metabolites, fatty acids, and polyhydroxyalkanoates were evaluated through untargeted metabolome analyses. Intracellular metabolomes during the degradation of phenanthrene were compared with those from natural carbon sources. Principal component analysis showed a clear separation of metabolomes of phenanthrene degradation from other carbon sources. Shift to more hydrophobic fatty acid was observed from the analysis of fatty acid methyl ester. Polyhydroxyalkanoate from strain C4 was composed mainly with 3-hydroxybutyric acid and small amount of 3-hydroxypentanoic acid, while the monomeric composition was independent on carbon sources. However, the amount of polyhydroxyalkanoates during degradation of phenanthrene was 50–210% less than those from other carbon sources. Among 207 gas chromatography–mass spectrometry peaks from the polar metabolite fraction, 60% of the peaks were identified and compared. Several intermediates in tricarboxylic acid cycles and glycolysis were increased during phenanthrene degradation. Accumulation of trehalose was also evident in the phenanthrene-treated bacterium. Some amino acid, including branched amino acids, glycine, homoserine, and valine, were also increased, while more than 70% of identified metabolites were decreased during the phenanthrene metabolism. Accumulation of sulfur amino acids and nicotinic acid suggested the possible oxidative stress conditions during phenanthrene metabolism.
has issue date	2008-10-01(xsd:dateTime)
bibo:doi	10.1007/s00253-008-1581-4
bibo:pmid	18668240
has license	cc-by-nc
sha1sum (hex)	fab940d8a68ebffa88eba7833777e73eae747333
schema:url	https://doi.org/10.1007/s00253-008-1581-4
resource representing a document's title	Comparative metabolomic analysis of Sinorhizobium sp. C4 during the degradation of phenanthrene
has PubMed Central identifier	PMC7419452
has PubMed identifier	18668240
schema:publication	Appl Microbiol Biotechnol
resource representing a document's body	covid:fab940d8a68ebffa88eba7833777e73eae747333#body_text
is schema:about of	named entity 'polyhydroxyalkanoates' named entity 'compared' named entity 'Comprehensive' named entity 'clear' named entity 'Sinorhizobium' named entity 'phenanthrene' named entity 'phenanthrene' named entity 'metabolism' named entity 'Comparative' named entity 'TREATED' named entity 'BACTERIUM' named entity 'ACCUMULATION' named entity 'EVALUATED' named entity 'INDEPENDENT' named entity 'SULFUR' named entity 'PHENANTHRENE METABOLISM' named entity 'CONDITIONS' named entity 'RESPONSES' covid:arg/fab940d8a68ebffa88eba7833777e73eae747333 named entity 'metabolome' named entity 'metabolic' named entity 'amino acids' named entity 'observed' named entity 'composition' named entity 'hydrophobic' named entity 'responses' named entity 'peaks' named entity 'glycine' named entity 'metabolic' named entity 'fatty acid' named entity 'carbon' named entity 'hydrophobic' named entity 'tricarboxylic acid' named entity 'polyhydroxyalkanoates' named entity 'fatty acid methyl ester' named entity 'metabolites' named entity 'Intracellular' named entity 'nicotinic acid' named entity 'fatty acids' named entity 'carbon' named entity 'phenanthrene' named entity 'phenanthrene' named entity 'metabolomic' named entity 'fatty acids' named entity 'aspartate' named entity 'Fatty acids' named entity 'intracellular' named entity 'metabolites' named entity 'fatty acid' named entity 'Bacterial cells' named entity 'Fisher Scientific' named entity 'Sweden' named entity 'long-chain' named entity 'BSTFA' named entity 'GC-MS' named entity 'biological systems' named entity 'genomics' named entity 'enzyme' named entity 'carbon' named entity 'secondary metabolism' named entity 'carbon source' named entity 'phenanthrene' named entity 'methanol' named entity 'catechol' named entity 'PCA' named entity 'microorganisms' named entity 'proteomics' named entity 'microorganisms' named entity 'metabolites' named entity 'hexose' named entity 'malate' named entity 'metabolomic' named entity 'hydrophobicity' named entity 'Sinorhizobium meliloti' named entity 'primary metabolism' named entity 'mutation' named entity 'carbon'

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