About: Hematological and Biochemical Factors Predicting SARS Fatality in Taiwan

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Hematological and Biochemical Factors Predicting SARS Fatality in Taiwan
Source	Elsevier; Medline; PMC
abstract	Background/Purpose Severe acute respiratory syndrome (SARS) has a high fatality rate worldwide. We examined the epidemiologic and clinical factors associated with death for all laboratory-confirmed SARS patients in Taiwan. Methods Using initial data in medical records reported by hospitals to the Center for Disease Control in Taiwan, we analyzed whether hematological, biochemical and arterial blood gas measures could predict fatality in 346 SARS patients. Results Both fatalities (n = 73; 21.1%) and survivors had elevated plasma concentration of initial C-reactive protein (CRP), but the mean CRP concentration was higher in fatalities (47.7 ± 43.3 mg/L) than in survivors (24.6 ± 28.2 mg/L). Initial lymphocyte counts were low in both fatalities (814 ± 378/μL) and survivors (1019 ± 480/μL). After controlling for age and sex, multiple logistic regression analysis showed that hematological factors significantly associated with fatality included initial neutrophil count > 7000/μL (odds ratio [OR] = 6.4), initial CRP concentration > 47.5 mg/L (OR = 5.8) and lactic acid dehydrogenase (LDH) > 593.5 IU/L (OR = 4.2). Factors significantly associated with initial CRP concentration > 47.5 mg/L included dyspnea (OR = 4.3), red blood cell count < 4.1 × 106/μL (OR = 4.3) and serum aspartate amino-transferase > 57 IU/L (OR = 3.1). Conclusion Initial neutrophil count, CRP and LDH levels are important predictors of mortality from SARS. [J Formos Med Assoc 2006;105(6):439-450]
has issue date	2006-12-31(xsd:dateTime)
bibo:doi	10.1016/s0929-6646(09)60183-2
bibo:pmid	16801031
has license	els-covid
sha1sum (hex)	fa5a49bad63e91934026cbcd22015989e3390d13
schema:url	https://doi.org/10.1016/s0929-6646%2809%2960183-2
resource representing a document's title	Hematological and Biochemical Factors Predicting SARS Fatality in Taiwan
has PubMed Central identifier	PMC7135597
has PubMed identifier	16801031
schema:publication	Journal of the Formosan Medical Association
resource representing a document's body	covid:fa5a49bad63e91934026cbcd22015989e3390d13#body_text
is schema:about of	named entity 'Methods' named entity 'mortality' named entity 'Severe acute respiratory syndrome (SARS)' named entity 'fatalities' named entity 'Disease Control' named entity 'hematological' named entity 'ASSOC' named entity 'ANALYZED' named entity '4.2' named entity 'WORLDWIDE' named entity 'SURVIVORS' named entity 'CENTER' named entity 'IMPORTANT' named entity 'HEMATOLOGICAL' named entity 'ELEVATED' named entity 'ASSOCIATED WITH' named entity 'METHODS' named entity '4.3' named entity 'SERUM' covid:arg/fa5a49bad63e91934026cbcd22015989e3390d13 named entity 'PATIENTS' named entity 'CONFIRMED' named entity 'LEVELS' named entity 'MEAN' named entity 'INITIAL' named entity 'EXAMINED' named entity 'BACKGROUND' named entity '5.8' named entity 'RATIO' named entity 'NEUTROPHIL COUNT' named entity 'LOGISTIC REGRESSION ANALYSIS' named entity 'BIOCHEMICAL' named entity '6.4' named entity 'TAIWAN' named entity 'MEDICAL RECORDS' named entity 'PROTEIN ' named entity 'LYMPHOCYTE COUNTS' named entity 'C-REACTIVE PROTEIN' named entity '4.1' named entity 'LOW' named entity 'CRP' named entity 'CONCENTRATION OF' named entity 'BUT' named entity 'LABORATORY' named entity '28814' named entity 'DATA' named entity 'LACTIC ACID DEHYDROGENASE' named entity 'RED BLOOD CELL COUNT' named entity 'MG%' named entity 'SARS' named entity 'MULTIPLE LOGISTIC REGRESSION' named entity 'RESULTS' named entity 'RATE' named entity 'INCLUDED' named entity 'PREDICT' named entity 'CONTROLLING' named entity 'EPIDEMIOLOGIC' named entity 'MEASURES' named entity 'SEVERE ACUTE RESPIRATORY SYNDROME' named entity 'ASPARTATE AMINOTRANSFERASE' named entity 'ARTERIAL BLOOD GAS' named entity 'USING' named entity 'DISEASE CONTROL' named entity 'MED' named entity 'AGE' named entity '7000' named entity 'BCL' named entity 'REPORTED BY' named entity 'HOSPITALS' named entity 'SEX' named entity 'DYSPNEA' named entity 'PLASMA CONCENTRATION' named entity '480' named entity '3.1' named entity 'DEATH' named entity 'CONCLUSION' named entity 'FATALITIES' named entity '450' named entity 'LDH' named entity 'HIGH' named entity 'MORTALITY' named entity 'CLINICAL'

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