About: Perspective on the host response to human metapneumovirus infection: what can we learn from respiratory syncytial virus infections?

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Perspective on the host response to human metapneumovirus infection: what can we learn from respiratory syncytial virus infections?
Creator	Nissen, Michael Sloots, Theo Alvarez, Rene Mahalingam, Surendran Schwarze, Jurgen Storer, James Tauro, Sharyn Zaid, Ali Tripp, Ralph
Source	Elsevier; Medline; PMC
abstract	Human metapneumovirus (HMPV) is a recently discovered pathogen first identified in respiratory specimens from young children suffering from clinical respiratory syndromes ranging from mild to severe lower respiratory tract illness. HMPV has worldwide prevalence, and is a leading cause of respiratory tract infection in the first years of life, with a spectrum of disease similar to respiratory syncytial virus (RSV). The disease burden associated with HMPV infection has not been fully elucidated; however, studies indicate that HMPV may cause upper or lower respiratory tract illness in patients between ages 2 months and 87 years, may co-circulate with RSV, and HMPV infection may be associated with asthma exacerbation. The mechanisms and effector pathways contributing to immunity or disease pathogenesis following infection are not fully understood; however, given the clinical significance of HMPV, there is a need for a fundamental understanding of the immune and pathophysiological processes that occur following infection to provide the foundation necessary for the development of effective vaccine or therapeutic intervention strategies. This review provides a current perspective on the processes associated with HMPV infection, immunity, and disease pathogenesis.
has issue date	2005-08-10(xsd:dateTime)
bibo:doi	10.1016/j.micinf.2005.07.001
bibo:pmid	16182587
has license	no-cc
sha1sum (hex)	f9705ccb796ba4f9957491623f765dfe8c5b4cf6
schema:url	https://doi.org/10.1016/j.micinf.2005.07.001
resource representing a document's title	Perspective on the host response to human metapneumovirus infection: what can we learn from respiratory syncytial virus infections?
has PubMed Central identifier	PMC7110670
has PubMed identifier	16182587
schema:publication	Microbes Infect
resource representing a document's body	covid:f9705ccb796ba4f9957491623f765dfe8c5b4cf6#body_text
is schema:about of	named entity 'PERSPECTIVE' named entity 'prevalence' named entity 'ages' named entity 'pathogen' named entity 'exacerbation' named entity 'suffering' named entity 'perspective' named entity 'VACCINE' named entity 'SPECTRUM' named entity 'PERSPECTIVE' named entity 'PATHOGEN' named entity 'UNDERSTANDING' named entity 'TO PROVIDE' named entity 'IS A' named entity 'REVIEW' named entity 'IDENTIFIED' named entity 'IMMUNITY' named entity 'HUMAN METAPNEUMOVIRUS' named entity 'INTERVENTION STRATEGIES' named entity 'FOUNDATION' named entity 'ASTHMA EXACERBATION' named entity 'A CURRENT' named entity 'ASSOCIATED WITH' named entity 'UPPER' named entity 'CAUSE' named entity 'PATHWAYS' named entity 'LEADING' named entity 'MAY BE' named entity 'SIMILAR' named entity 'WORLDWIDE' named entity 'HOST RESPONSE' named entity 'WHAT' named entity 'RESPIRATORY SYNCYTIAL VIRUS INFECTIONS' named entity 'RESPONSE TO' named entity 'LEARN' named entity 'YEARS' named entity 'NEED FOR' named entity 'LOWER RESPIRATORY TRACT' named entity 'ILLNESS' named entity 'CLINICAL' named entity 'EFFECTOR' named entity 'INFECTION' named entity 'DISEASE' named entity 'RSV' named entity 'RESPIRATORY SYNCYTIAL VIRUS' named entity 'LIFE' named entity 'HUMAN METAPNEUMOVIRUS INFECTION' named entity 'PATHOGENESIS' named entity 'CONTRIBUTING' named entity 'GIVEN' named entity 'RESPIRATORY' named entity 'OCCUR' named entity 'PATIENTS' named entity 'SEVERE' named entity 'MONTHS' named entity 'FOLLOWING' named entity 'AGES' named entity 'SYNDROMES' named entity 'PREVALENCE' named entity 'CIRCULATE' named entity 'NECESSARY' named entity 'RECENTLY' named entity 'CLINICAL SIGNIFICANCE' named entity 'THERAPEUTIC INTERVENTION' named entity 'YOUNG CHILDREN' named entity 'SUFFERING' named entity 'DEVELOPMENT' named entity 'BURDEN' named entity 'FULLY' named entity 'PROCESSES' named entity 'MILD' named entity 'SPECIMENS' named entity 'MECHANISMS'

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