About: Identification of cell lines permissive for human coronavirus NL63

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Identification of cell lines permissive for human coronavirus NL63
Creator	Dijkman, Ronald Kupfer, Bernd Müller, Andreas Schildgen, Oliver Simon, Arne Jebbink, Maarten De Vries, Michel Van Der Hoek, Lia Pyrc, Krzysztov
Source	Elsevier; Medline; PMC
abstract	Six cell lines routinely used in laboratories were tested for permissiveness to the infection with the newly identified human coronavirus NL63. Two monkey epithelial cell lines, LLC-MK2 and Vero-B4, showed a cytopathic effect (CPE) and clear viral replication, whereas no CPE or replication was observed in human lung fibroblasts MRC-5s. In Rhabdomyosarcoma cells, Madin–Darby–Canine-kidney cells and in an undefined monkey kidney cell line some replication was observed but massive exponential rise in virus yield lacked The results will lead to an improved routine diagnostic algorithm for the detection of the human coronavirus NL63.
has issue date	2006-09-07(xsd:dateTime)
bibo:doi	10.1016/j.jviromet.2006.07.023
bibo:pmid	16962670
has license	no-cc
sha1sum (hex)	f927a30342bb541a01402fe10e981658c9c5d536
schema:url	https://doi.org/10.1016/j.jviromet.2006.07.023
resource representing a document's title	Identification of cell lines permissive for human coronavirus NL63
has PubMed Central identifier	PMC7112796
has PubMed identifier	16962670
schema:publication	J Virol Methods
resource representing a document's body	covid:f927a30342bb541a01402fe10e981658c9c5d536#body_text
is schema:about of	named entity 'CELL LINES' named entity 'virus' named entity 'Rhabdomyosarcoma' named entity 'CELLS' named entity 'VERO-B4' named entity 'FIBROBLASTS' named entity 'LLC' named entity 'TESTED FOR' named entity 'YIELD' named entity 'LABORATORIES' named entity 'MASSIVE' named entity 'RHABDOMYOSARCOMA' named entity 'HUMAN CORONAVIRUS NL63' covid:arg/f927a30342bb541a01402fe10e981658c9c5d536 named entity 'HUMAN CORONAVIRUS NL63' named entity 'IDENTIFICATION' named entity 'DIAGNOSTIC ALGORITHM' named entity 'RISE' named entity 'VIRUS' named entity 'KIDNEY' named entity 'CPE' named entity 'EXPONENTIAL' named entity 'CYTOPATHIC EFFECT' named entity 'KIDNEY CELL LINE' named entity 'DETECTION' named entity 'USED' named entity 'EPITHELIAL CELL' named entity 'CELL LINES' named entity 'OBSERVED' named entity 'BUT' named entity 'IMPROVED' named entity 'RESULTS' named entity 'MONKEY' named entity 'HUMAN LUNG' named entity 'IDENTIFIED' named entity 'PERMISSIVENESS' named entity 'CANINE' named entity 'CLEAR' named entity 'MRC' named entity 'ROUTINE' named entity 'VIRAL REPLICATION' named entity 'REPLICATION' named entity 'MK2' named entity 'UNDEFINED' named entity 'LEAD' named entity 'NEWLY' named entity 'INFECTION' named entity 'lines' named entity 'replication' named entity 'undefined' named entity 'lead' named entity 'CPE' named entity 'cell lines' named entity 'MRC-5' named entity 'virus' named entity 'viewed under a microscope' named entity 'Human lung' named entity 'negative control' named entity 'fibroblast' named entity 'Invitrogen' named entity 'NL63' named entity 'FCS' named entity 'cytopathic effects' named entity 'RNA' named entity 'MDCK' named entity 'genomes' named entity 'SARS coronavirus' named entity 'viral replication' named entity 'rise' named entity 'infection' named entity 'NL63' named entity 'human coronavirus' named entity 'Canine'

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