About: Characterization of haemagglutinin-neuraminidase glycoprotein of Newcastle disease virus expressed by a recombinant baculovirus

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About: Characterization of haemagglutinin-neuraminidase glycoprotein of Newcastle disease virus expressed by a recombinant baculovirus Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Characterization of haemagglutinin-neuraminidase glycoprotein of Newcastle disease virus expressed by a recombinant baculovirus
Creator	Matsuura, Yoshiharu Hattori ', Masakazu Mikami, Takeshi Niikura ', Masahiro Onuma ', Misao
source	Elsevier; PMC
abstract	Abstract A recombinant baculovirus containing a cDNA which encodes haemagglutinin-neuraminidase (HN) of Newcastle disease virus (NDV) was constructed. Spodoptera frugiperda cells infected with this recombinant virus produced a large amount of HN glycoprotein similar to the authentic HN in size. The recombinant HN glycoprotein was localized on the surface of the infected cells and conserved its haemadsorption and neuraminidase activities. The antigenic properties of the recombinant HN glycoprotein seemed to be slightly different from the authentic one, as judging by the reactivity with a panel of monoclonal antibodies specific to the antigenic sites responsible for neutralization of viral infectivity. Chickens inoculated with the cells infected with the recombinant virus developed haemagglutination-inhibition and virus neutralization antibodies, and were completely protected from the NDV challenge.
has issue date	1991-06-30(xsd:dateTime)
bibo:doi	10.1016/0168-1702(91)90059-5
bibo:pmid	1927050
has license	els-covid
sha1sum (hex)	f83950a0ebd06ef4f1da62f1785651ad83188ea9
schema:url	https://doi.org/10.1016/0168-1702%2891%2990059-5
resource representing a document's title	Characterization of haemagglutinin-neuraminidase glycoprotein of Newcastle disease virus expressed by a recombinant baculovirus
has PubMed Central identifier	PMC7134041
has PubMed identifier	1927050
schema:publication	Virus Research
resource representing a document's body	covid:f83950a0ebd06ef4f1da62f1785651ad83188ea9#body_text
is schema:about of	named entity 'SLIGHTLY' named entity 'RESPONSIBLE' named entity 'RECOMBINANT' named entity 'CHARACTERIZATION' named entity 'SITES' named entity 'CDNA' named entity 'PROPERTIES' named entity 'INFECTED' named entity 'CONTAINING' named entity 'CONSTRUCTED' named entity 'DIFFERENT' named entity 'VIRUS NEUTRALIZATION' named entity 'GLYCOPROTEIN' named entity 'SIZE' named entity 'RECOMBINANT VIRUS' named entity 'VIRAL' named entity 'HAEMAGGLUTINATION' named entity 'NEURAMINIDASE' named entity 'BACULOVIRUS' named entity 'EXPRESSED' named entity 'NEWCASTLE DISEASE VIRUS' named entity 'CHALLENGE' named entity 'MONOCLONAL ANTIBODIES' named entity 'JUDGING' named entity 'INFECTIVITY' named entity 'CELLS' named entity 'HAEMADSORPTION' named entity 'BACULOVIRUS' named entity 'CHICKENS' named entity 'CONSERVED' named entity 'COMPLETELY' named entity 'INHIBITION' named entity 'LOCALIZED' named entity 'ITS' named entity 'HAEMAGGLUTININ' named entity 'LARGE AMOUNT' named entity 'ANTIBODIES' named entity 'PANEL' named entity 'RECOMBINANT' named entity 'ANTIBODIES SPECIFIC' named entity 'NEURAMINIDASE' named entity 'ACTIVITIES' named entity 'REACTIVITY' named entity 'NEWCASTLE DISEASE VIRUS' named entity 'SURFACE' named entity 'SIMILAR' named entity 'GLYCOPROTEIN' covid:arg/f83950a0ebd06ef4f1da62f1785651ad83188ea9 named entity 'recombinant' named entity 'glycoprotein' named entity 'Newcastle disease' named entity 'baculovirus' named entity 'neuraminidase' named entity 'monoclonal antibodies' named entity 'glycoprotein' named entity 'glycoprotein' named entity 'glycoprotein' named entity 'neuraminidase' named entity 'molecular property' named entity 'neutralization tests' named entity 'recombinant' named entity 'recombinant' named entity 'functional analysis' named entity 'supernatants' named entity 'digestion' named entity 'N-linked glycosylation sites' named entity 'NDV' named entity 'recombinant' named entity '35 mm' named entity 'recombinant' named entity 'Takara Shuzo' named entity 'mAbs' named entity 'recombinant' named entity 'infectivity' named entity 'recombinant' named entity 'recombinant' named entity 'Spodoptera frugiperda'

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