About: Current Insight into the Novel Coronavirus Disease 2019 (COVID-19)

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Current Insight into the Novel Coronavirus Disease 2019 (COVID-19)
Creator	Kumar, Swatantra Sharma, R Bhatt, Madan Kumar, S Bhatt, · Dandu, H Dandu, Himanshu Maurya, Vimal Maurya, V Saxena, Shailendra Saxena, S Sharma, Raman
source	PMC
abstract	SARS-CoV-2 is a novel strain of coronavirus that has not been previously identified in humans. It has been declared a pandemic and has infected at least 1,844,683 individuals and caused 117,021 deaths as of 14th April 2020. Transmission among humans occurs via close contact with an infected individual that produces respiratory droplets. Patients have been shown to undergo acute respiratory distress syndrome, which is defined as cytokine storm. The diagnosis relies on detection of nucleic acid, IgG/IgM antibodies, and a chest radiograph of the suspected individuals. The genome of SARS-CoV-2 is similar to other coronaviruses that comprise of ten open reading frames (ORFs). SARS-CoV-2 spike protein exhibits higher affinity to ACE2 receptor as compared with SARS-CoV. Repurposing drugs like favipiravir, remdesivir, chloroquine, and TMPRSS2 protease inhibitors have been shown to be effective for the treatment of COVID-19. Personal protective measures should be followed to prevent SARS-CoV-2 infection. In addition, a clinical trial of SARS-CoV-2 vaccine, mRNA-1273, has been started. This chapter provides a glimpse of advancements made in the area of SARS-CoV-2 infection by proving recent clinical and research trials in the field.
has issue date	2020-04-30(xsd:dateTime)
bibo:doi	10.1007/978-981-15-4814-7_1
has license	no-cc
sha1sum (hex)	f6a1e73ea49148dfae725e20501abeac994fe4ae
schema:url	https://doi.org/10.1007/978-981-15-4814-7_1
resource representing a document's title	Current Insight into the Novel Coronavirus Disease 2019 (COVID-19)
has PubMed Central identifier	PMC7189397
schema:publication	Coronavirus Disease 2019 (COVID-19)
resource representing a document's body	covid:f6a1e73ea49148dfae725e20501abeac994fe4ae#body_text
is schema:about of	named entity 'acute respiratory distress syndrome' named entity 'SARS-CoV-2' named entity 'contact' named entity 'infection' named entity 'suspected' named entity 'SIMILAR' named entity 'INDIVIDUAL' named entity 'TMPRSS2' named entity 'CHLOROQUINE' named entity 'CAUSED' named entity 'CHEST RADIOGRAPH' named entity 'TREATMENT' named entity 'RESEARCH' named entity 'coronaviruses' named entity 'chloroquine' named entity 'infected' named entity 'strain' named entity 'addition' named entity 'individuals' named entity 'individual' named entity 'SARS-CoV-2' named entity 'individuals' named entity 'effective' named entity 'This' named entity 'Patients' named entity 'infection' named entity 'SARS-CoV-2' named entity 'open reading frames' named entity 'chest radiograph' named entity 'SARS-CoV-2' named entity 'spike protein' named entity 'ORFs' named entity 'vaccine' named entity 'TMPRSS2' named entity 'previously identified' named entity 'detection' named entity 'prevent the spread' named entity 'SARS-CoV-2' named entity 'SARS-CoV-2' named entity 'IgM' named entity 'lung' named entity 'SARS-CoV-2' named entity 'immunological' named entity 'chemokines' named entity 'COVID' named entity 'infection' named entity 'protease inhibitors' named entity 'IL-18' named entity 'COVID' named entity 'infection' named entity 'genome' named entity 'leukocyte' named entity 'non-structural proteins' named entity 'infection' named entity 'cytokine storm syndrome' named entity 'open reading frames' named entity 'SARS-CoV-2' named entity 'coronavirus' named entity 'COVID' named entity 'virus' named entity 'RT-qPCR' named entity 'SARS-CoV-2' named entity 'intestine' named entity 'coughing' named entity 'repurposing drugs' named entity 'type II' named entity 'nasopharyngeal' named entity 'sneezing' named entity '2019-nCoV' named entity 'WHO' named entity 'bioinformatics' named entity 'severe acute respiratory syndrome coronavirus 2'

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