About: Epidemiology and Clinical Presentation of Children Hospitalized with SARS-CoV-2 Infection in Suburbs of Paris

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About: Epidemiology and Clinical Presentation of Children Hospitalized with SARS-CoV-2 Infection in Suburbs of Paris Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Epidemiology and Clinical Presentation of Children Hospitalized with SARS-CoV-2 Infection in Suburbs of Paris
Creator	Epaud, Ralph Varon, Emmanuelle Ducrocq, Sarah Madhi, Fouad Nathanson, Sylvie Aal, Khaled Barrey, Catherine Bensaid, Philippe Blanc, Philippe Chahine, Jamilé Chalvon, Arnaud Delestrain, Celine Demayer, Nadia Gaborieau, Louise Garraffo, Aurélie Garrec, Nathalie Georget, Emilie Joly-Sanchez, Lydie Khaled, Mohamed Laoudi, Yacine Mandelcwajg, Alexis Masserot-Lureau, Caroline Mazerghane, Mustapha Muller, Stéphanie Pantalone, Letitia Pellegrino, Béatrice Pupin, Alexandre Risso Garcia-Roudaut, Veronica Robert, Blandine Rouget, Sébastien Rozental, Jonathan Thach, Caroline Toulorge, David Vizeneux, Audrey
Source	Medline; PMC
abstract	Understanding the clinical presentation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and prognosis in children is a major issue. Children often present mild symptoms, and some severe forms require paediatric intensive care, with in some cases a fatal prognosis. Our aim was to identify the epidemiological characteristics, clinical presentation, and prognosis of children with coronavirus disease 2019 (Covid-19) hospitalized in Paris suburb hospitals. In this prospective, observational, multicentre study, we included children hospitalized in paediatric departments of Paris suburb hospitals from 23 March 2020 to 10 May 2020, during the national lockdown in France with confirmed SARS-CoV-2 infection (positive RNA test on a nasopharyngeal swab) or highly suspected infection (clinical, biological, and/or radiological data features suggestive for SARS-CoV-2 infection). A total of 192 children were included for confirmed (n = 157) or highly suspected (n = 35) SARS-CoV-2 infection. The median age was one year old (interquartile range 0.125–11) with a sex ratio 1.3:1. Fever was recorded in 147 (76.6%) children and considered poorly tolerated in 29 (15.1%). The symptoms ranged from rhinorrhoea (34.4%) and gastrointestinal (35.5%) to respiratory distress (25%). Only 10 (5.2%) children had anosmia and five (2.6%) had chest pain. An underlying condition was identified in almost 30% of the children in our study. Overall, 24 (12.5%) children were admitted to paediatric intensive care units, 12 required mechanical ventilation, and three died. For children in Paris suburbs, most cases of Covid-19 showed mild or moderate clinical expression. However, one-eighth of children were admitted to paediatric intensive care units and three died.
has issue date	2020-07-14(xsd:dateTime)
bibo:doi	10.3390/jcm9072227
bibo:pmid	32674306
has license	cc-by
sha1sum (hex)	f6478ea3d064531d88bf4ea762c20fd83a5bdd26
schema:url	https://doi.org/10.3390/jcm9072227
resource representing a document's title	Epidemiology and Clinical Presentation of Children Hospitalized with SARS-CoV-2 Infection in Suburbs of Paris
has PubMed Central identifier	PMC7408757
has PubMed identifier	32674306
schema:publication	J Clin Med
resource representing a document's body	covid:f6478ea3d064531d88bf4ea762c20fd83a5bdd26#body_text
is schema:about of	named entity 'suburbs' named entity 'suburb' named entity 'prospective' named entity 'cases' named entity 'identify' named entity 'interquartile range' named entity 'highly' named entity 'rhinorrhoea' named entity 'data' named entity 'Paris' named entity 'Suburbs' named entity 'EIGHTH' named entity 'UNDERSTANDING' named entity 'OBSERVATIONAL' named entity 'SYMPTOMS' named entity 'PROGNOSIS' named entity 'CHARACTERISTICS' named entity 'RNA' named entity 'ADMITTED TO' named entity 'suburb' named entity 'Paris' named entity 'features' named entity 'prognosis' named entity 'suggestive' named entity 'cases' named entity 'study' named entity 'identified' named entity 'presentation' named entity 'national' named entity 'respiratory distress' named entity 'fatal' named entity 'study' named entity 'gastrointestinal' named entity 'Paris' named entity 'died' named entity 'paediatric' named entity 'Clinical Medicine' named entity 'prognosis' named entity 'Covid-19' named entity 'paediatric intensive care' named entity 'clinical presentation' named entity 'SARS-CoV-2' named entity 'epidemiological' named entity 'mechanical ventilation' named entity 'national lockdown' named entity 'infection' named entity 'severe acute respiratory syndrome coronavirus 2' named entity 'anosmia'

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