About: Evidence favouring the efficacy of convalescent plasma for COVID-19 therapy

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About: Evidence favouring the efficacy of convalescent plasma for COVID-19 therapy Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Evidence favouring the efficacy of convalescent plasma for COVID-19 therapy
Creator	Casadevall, Arturo Pirofski, Liise-Anne Shoham, Shmuel Wright, R Bouvier, Nicole Musser, James Fairweather, Delisa Henderson, Jeffrey Liu, Sean Paneth, Nigel Salazar, Eric Hartman, William Baker, Sarah Bruno, Katelyn Carter, Rickey Johnson, Patrick Joyner, Michael Klassen, Stephen Senefeld, Jonathon Wiggins, Chad Grossman, Brenda Van Helmond, Noud
Source	MedRxiv
abstract	To determine the effect of COVID-19 convalescent plasma on mortality, we aggregated patient outcome data from randomized clinical trials, matched control, and case-series studies. Fixed-effects analyses demontrated that hospitalized COVID-19 patients transfused with convalescent plasma exhibited a a57% reduction in mortality rate (13%) compared to matched-patients receiving standard treatments (25%; OR: 0.43, P < 0.001). These data provide evidence favouring the efficacy of human convalescent plasma as a therapeutic agent in hospitalized COVID-19 patients.
has issue date	2020-07-30(xsd:dateTime)
bibo:doi	10.1101/2020.07.29.20162917
has license	medrxiv
sha1sum (hex)	f5b28c07753eeb5ee3ca3a3d0619663f14dc9f00
schema:url	https://doi.org/10.1101/2020.07.29.20162917
resource representing a document's title	Evidence favouring the efficacy of convalescent plasma for COVID-19 therapy
resource representing a document's body	covid:f5b28c07753eeb5ee3ca3a3d0619663f14dc9f00#body_text
is schema:about of	named entity 'efficacy' named entity 'human' named entity 'agent' named entity 'convalescent' named entity 'convalescent' named entity 'All rights reserved' named entity 'compared' named entity 'COVID-19' named entity 'COVID' named entity 'randomized clinical trials' named entity 'COVID' named entity 'COVID' named entity 'outlier' named entity 'COVID-19' named entity 'regression analyses' named entity 'odds ratios' named entity 'patient outcomes' named entity 'case series' named entity 'odds ratios' named entity 'mortality rate' named entity 'odds ratios' named entity 'odds ratios' named entity 'SARS-CoV-2' named entity 'fixed effect' named entity 'preprint' named entity 'mortality rate' named entity 'COVID-19' named entity 'randomized clinical trials' named entity 'convalescent plasma' named entity 'COVID' named entity 'medRxiv' named entity 'COVID-19' named entity 'coronavirus disease 2019' named entity 'convalescent plasma therapy' named entity 'Mortality rates' named entity 'COVID' named entity 'COVID-19' named entity 'COVID' named entity 'antibody titer' named entity 'convalescent plasma' named entity 'COVID' named entity 'mechanical ventilation' named entity 'bacterial meningitis' named entity 'controlled studies' named entity 'mortality rates' named entity 'COVID-19 pandemic' named entity 'preprint' named entity 'influenza' named entity 'controlled studies' named entity 'convalescent plasma' named entity 'mortality rate' named entity 'viral diseases' named entity 'COVID' named entity 'convalescent plasma' named entity 'pneumonia' named entity 'COVID' named entity 'infectious diseases' named entity 'odds ratios' named entity 'plasma' named entity 'pre-print' named entity 'COVID-19' named entity 'plasma' named entity 'antibody-mediated' named entity 'COVID'

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