About: More than one door – Budding of enveloped viruses through cellular membranes

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	More than one door – Budding of enveloped viruses through cellular membranes
Creator	Welsch, Sonja Kräusslich, Hans-Georg Mü, Barbara
source	Elsevier; Medline; PMC
abstract	Enveloped viruses exit their host cell by budding from a cellular membrane and thereby spread from one cell to another. Virus budding in general involves the distortion of a cellular membrane away from the cytoplasm, envelopment of the viral capsid by one or more lipid bilayers that are enriched in viral membrane glycoproteins, and a fission event that separates the enveloped virion from the cellular membrane. While it was initially thought that virus budding is always driven by viral transmembrane proteins interacting with the inner structural proteins, it is now clear that the driving force may be different depending on the virus. Research over the past years has shown that viral components specifically interact with host cell lipids and proteins, thereby adopting cellular functions and pathways to facilitate virus release. This review summarizes the current knowledge of the cellular membrane systems that serve as viral budding sites and of the viral and cellular factors involved in budding. One of the best studied cellular machineries required for virus egress is the ESCRT complex, which will be described in more detail.
has issue date	2007-05-22(xsd:dateTime)
bibo:doi	10.1016/j.febslet.2007.03.060
bibo:pmid	17434167
has license	no-cc
sha1sum (hex)	f513f58f3b0468656b956aa6067d15e744edb486
schema:url	https://doi.org/10.1016/j.febslet.2007.03.060
resource representing a document's title	More than one door – Budding of enveloped viruses through cellular membranes
has PubMed Central identifier	PMC7126970
has PubMed identifier	17434167
schema:publication	FEBS Lett
resource representing a document's body	covid:f513f58f3b0468656b956aa6067d15e744edb486#body_text
is schema:about of	named entity 'ESCRT' named entity 'budding' named entity 'bilayers' named entity 'cellular' named entity 'More' named entity 'PATHWAYS' named entity 'BEST' named entity 'THOUGHT' named entity 'STRUCTURAL PROTEINS' named entity 'ADOPTING' named entity 'INNER' named entity 'INITIALLY' named entity 'RESEARCH' named entity 'LIPID BILAYERS' named entity 'VIRUS BUDDING' named entity 'VIRAL AND' named entity 'TRANSMEMBRANE PROTEINS' named entity 'KNOWLEDGE' named entity 'HOST CELL' named entity 'MORE THAN ONE' named entity 'VIRAL MEMBRANE' named entity 'VIRUS RELEASE' named entity 'SPREAD' named entity 'DIFFERENT' named entity 'DOOR' named entity 'REQUIRED' named entity 'FORCE' named entity 'FUNCTIONS' named entity 'MEMBRANE SYSTEMS' named entity 'MEMBRANES' named entity 'CELLULAR' named entity 'ONE CELL' named entity 'CYTOPLASM' named entity 'SERVE' named entity 'INTERACTING' named entity 'VIRAL' named entity 'DRIVING' named entity 'LIPIDS' named entity 'CURRENT' named entity 'THEIR' named entity 'ONE OF' named entity 'INVOLVED' named entity 'PROTEINS' named entity 'AWAY' named entity 'BUDDING' named entity 'FISSION' named entity 'SITES' named entity 'DRIVEN' named entity 'CLEAR' named entity 'VIRION' named entity 'MAY BE' named entity 'DESCRIBED' named entity 'REVIEW' named entity 'GENERAL' named entity 'DISTORTION' named entity 'ENRICHED' named entity 'PAST' named entity 'CELLULAR MEMBRANE' named entity 'VIRUSES' named entity 'EXIT' named entity 'EVENT' named entity 'INTERACT' named entity 'VIRUS' named entity 'VIRAL COMPONENTS' named entity 'CELLULAR' named entity 'VIRAL CAPSID' named entity 'YEARS' named entity 'BUDDING' named entity 'VIRUSES' named entity 'ESCRT COMPLEX' named entity 'MEMBRANE GLYCOPROTEINS' named entity 'cell' named entity 'summarizes' named entity 'machineries' named entity 'virus' named entity 'detail' named entity 'virus' named entity 'viral' named entity 'adopting'

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