About: Evaluation of nasopharyngeal swab collection techniques for nucleic acid recovery and participant experience: recommendations for COVID-19 diagnostics

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About: Evaluation of nasopharyngeal swab collection techniques for nucleic acid recovery and participant experience: recommendations for COVID-19 diagnostics Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Evaluation of nasopharyngeal swab collection techniques for nucleic acid recovery and participant experience: recommendations for COVID-19 diagnostics
Creator	Stefanovic, Aleksandra Lowe, Christopher Brumme, Zabrina Dong, Winnie Kinloch, Natalie Lawson, Tanya Leung, Victor Matic, Nancy Romney, Marc Ritchie, Brumme, Montaner, S Shahid,
Source	MedRxiv
abstract	Nasopharyngeal swabs are critical to the diagnosis of respiratory infections including COVID-19, but collection techniques vary. We compared two recommended nasopharyngeal swab collection techniques in adult volunteers and found that swab rotation following nasopharyngeal contact did not recover additional nucleic acid (as measured by human DNA/RNA copy number). Rotation was also less tolerable for participants. Notably, both discomfort and nucleic acid recovery were significantly higher in Asians, consistent with nasal anatomy differences. Our results suggest that it is unnecessary to rotate the swab in place following contact with the nasopharynx, and reveal that procedural discomfort levels can differ by ethnicity.
has issue date	2020-08-25(xsd:dateTime)
bibo:doi	10.1101/2020.08.18.20177592
has license	medrxiv
sha1sum (hex)	f4b7c4ca12c4b081e15bf8cc166ba00ed6f42986
schema:url	https://doi.org/10.1101/2020.08.18.20177592
resource representing a document's title	Evaluation of nasopharyngeal swab collection techniques for nucleic acid recovery and participant experience: recommendations for COVID-19 diagnostics
resource representing a document's body	covid:f4b7c4ca12c4b081e15bf8cc166ba00ed6f42986#body_text
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