About: Diagnostic and therapeutic approach to infectious diseases in solid organ transplant recipients

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Diagnostic and therapeutic approach to infectious diseases in solid organ transplant recipients
Creator	Papazian, Laurent Timsit, Jean-François Bassetti, Matteo Jaber, Samir Lanternier, Fanny Wolff, Michel Mikulska, Malgorzata Viscoli, Claudio Sonneville, Romain Luyt, Charles-Edouard Ferrer, Ricard Kalil, Andre Delden, Christian Machado, Flavia Poulakou, Garyphalia Pène, Fréderic Zafrani, Lara
source	Medline; PMC
abstract	PURPOSE: Prognosis of solid organ transplant (SOT) recipients has improved, mainly because of better prevention of rejection by immunosuppressive therapies. However, SOT recipients are highly susceptible to conventional and opportunistic infections, which represent a major cause of morbidity, graft dysfunction and mortality. METHODS: Narrative review. RESULTS: We cover the current epidemiology and main aspects of infections in SOT recipients including risk factors such as postoperative risks and specific risks for different transplant recipients, key points on anti-infective prophylaxis as well as diagnostic and therapeutic approaches. We provide an up-to-date guide for management of the main syndromes that can be encountered in SOT recipients including acute respiratory failure, sepsis or septic shock, and central nervous system infections as well as bacterial infections with multidrug-resistant strains, invasive fungal diseases, viral infections and less common pathogens that may impact this patient population. CONCLUSION: We provide state-of the art review of available knowledge of critically ill SOT patients with infections.
has issue date	2019-03-25(xsd:dateTime)
bibo:doi	10.1007/s00134-019-05597-y
bibo:pmid	30911807
has license	no-cc
sha1sum (hex)	f161a1dd8264dd1dd6e094d5b2cfc3d866fab1b9
schema:url	https://doi.org/10.1007/s00134-019-05597-y
resource representing a document's title	Diagnostic and therapeutic approach to infectious diseases in solid organ transplant recipients
has PubMed Central identifier	PMC7079836
has PubMed identifier	30911807
schema:publication	Intensive Care Med
resource representing a document's body	covid:f161a1dd8264dd1dd6e094d5b2cfc3d866fab1b9#body_text
is schema:about of	named entity 'SOT' named entity 'represent' named entity 'MORTALITY' named entity 'morbidity' named entity 'immunosuppressive' named entity 'morbidity' named entity 'solid organ transplant' named entity 'solid organ transplant' named entity 'aspergillosis' named entity 'SOT' named entity 'infection' named entity 'immunosuppressive agents' named entity 'empirical treatment' named entity 'SOT' named entity 'prophylaxis' named entity 'surgical site infections' named entity 'Drug interactions' named entity 'CNS' named entity 'organ' named entity 'relative risk' named entity 'CMV' named entity 'M. marinum' named entity 'causing disease' named entity 'oseltamivir' named entity 'respiratory infection' named entity 'peritonitis' named entity 'etiology' named entity 'infection' named entity 'Toxoplasma' named entity 'immunosuppression' named entity 'lung transplants' named entity 'gram-negative bacilli' named entity 'vesico-ureteral reflux' named entity 'infection' named entity 'Calcineurin inhibitors' named entity 'preventive measures' named entity 'lung transplant' named entity 'Maquet' named entity 'pathogens' named entity 'hemorrhagic' named entity 'hepatitis' named entity 'virus' named entity 'surgical phase' named entity 'fungal infections' named entity 'organ' named entity 'oseltamivir' named entity 'immunosuppression' named entity 'immunocompromised patients' named entity 'ICU' named entity 'ischemic' named entity 'primary graft dysfunction' named entity 'SOT' named entity 'CMV' named entity 'liver transplant' named entity 'infection' named entity 'Jazz Pharmaceuticals' named entity 'immunosuppression' named entity 'CMV disease' named entity 'prophylaxis' named entity 'valganciclovir' named entity 'prophylaxis' named entity 'linezolid' named entity 'abscesses' named entity 'viral load' named entity 'morbidity'

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