About: Studies on avian infectious bronchitis virus (IBV): III. Interferon induction by and sensitivity to interferon of IBV

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Studies on avian infectious bronchitis virus (IBV): III. Interferon induction by and sensitivity to interferon of IBV
Creator	Maeda, J O~suki, K Tsubokura, Yamai~oto, M
Source	PMC
abstract	The induction of interferon by avian infectious bronchitis virus (IBV) and the sensitivity of IBV to interferon were studied. The results of experiments with ten IBV strains are summarized as follows. 1. All the IBV strains tested induced interferon in chick embryo (CE) cells, chicken kidney (CK) cells and embryonated eggs. The Iowa-609 strain induced about 1000 units of interferon in CE cells while the Beaudette-42 strain induced about 200 units of interferon in embryonated eggs; the interferon titers induced by other strains usually ranged from 5 to 60 units. No IBV strain induced interferon in HeLa or BHK-21 cells. 2. IBV particles inactivated by ultraviolet irradiation or by heating lost their ability to induce interferon. 3. The properties of the interferon produced in the present study are similar to those of other interferons produced in chicken cells. 4. HeLa or BHK-21 cells did not acquire resistance to virus infection, after incubation with interferon produced in CE cells. On the other hand, CK cells acquired the same degree of resistance to virus infection as CE cells after incubation with interferon produced in CE cells. 5. All the IBV strains tested were sensitive to interferon in CK cells. The sensitivities of Massachusetts-41 and Holte strains to interferon were similar to that of vesicular stomatitis virus.
has issue date	1979-01-01(xsd:dateTime)
bibo:doi	10.1007/bf01317496
bibo:pmid	228636
has license	no-cc
sha1sum (hex)	ef9e5d3478a25dc6971c9013a57eebff7747ac19
schema:url	https://doi.org/10.1007/bf01317496
resource representing a document's title	Studies on avian infectious bronchitis virus (IBV): III. Interferon induction by and sensitivity to interferon of IBV
has PubMed Central identifier	PMC7087316
has PubMed identifier	228636
schema:publication	Arch Virol
resource representing a document's body	covid:ef9e5d3478a25dc6971c9013a57eebff7747ac19#body_text
is schema:about of	named entity 'sensitivity' named entity 'strains' named entity 'interferon' named entity 'virus' named entity 'heating' named entity 'Holte' named entity 'Virology' named entity 'Avian' named entity 'INCUBATION' named entity 'PRESENT' named entity 'ABOUT' named entity 'USUALLY' named entity 'CHICKEN' named entity 'KIDNEY' named entity 'INDUCE' named entity 'AVIAN INFECTIOUS BRONCHITIS VIRUS' named entity 'RESULTS' named entity 'HOLTE' named entity 'INDUCTION' named entity 'RESISTANCE TO' named entity 'TESTED' named entity 'VIRUS INFECTION' named entity 'SIMILAR' named entity 'THEIR' covid:arg/ef9e5d3478a25dc6971c9013a57eebff7747ac19 named entity 'DID' named entity 'STRAIN' named entity 'STRAINS' named entity 'INDUCED' named entity 'SENSITIVITY' named entity 'HELA' named entity 'CHICK EMBRYO' named entity 'INTERFERON ' named entity 'STUDY' named entity 'CELLS' named entity 'SENSITIVITY' named entity 'ARCHIVES' named entity 'HAND' named entity 'FOLLOWS' named entity '200' named entity 'IOWA' named entity 'INTERFERONS' named entity 'ACQUIRED' named entity 'INDUCTION' named entity 'ILL' named entity 'VIROLOGY' named entity 'INTERFERON ' named entity 'STUDIES' named entity 'EGGS' named entity '1000' named entity 'PARTICLES' named entity 'SENSITIVE TO' named entity 'AVIAN INFECTIOUS BRONCHITIS VIRUS' named entity 'HEATING' named entity 'PROPERTIES' named entity 'UNITS' named entity 'CHICKEN CELLS' named entity 'EXPERIMENTS' named entity 'LOST' named entity 'BHK-21' named entity 'INTERFERON' named entity '609' named entity 'DEGREE' named entity 'MASSACHUSETTS' named entity 'ACQUIRE' named entity 'VESICULAR STOMATITIS VIRUS' named entity 'INACTIVATED' named entity 'ULTRAVIOLET IRRADIATION' named entity 'induced' named entity 'interferon' named entity 'acquired' named entity 'ultraviolet' named entity 'tested' named entity 'acquire' named entity 'experiments' named entity 'produced' named entity 'IBV' named entity 'IBV'

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