About: Clinical Profile of Critical Pertussis in Children at a Pediatric Intensive Care Unit in Northern India

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About: Clinical Profile of Critical Pertussis in Children at a Pediatric Intensive Care Unit in Northern India Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Clinical Profile of Critical Pertussis in Children at a Pediatric Intensive Care Unit in Northern India
Creator	Gautam, Vikas Jayashree, Muralidharan Kavitha, T Samprathi, Madhusudan Sangal, Lucky
Source	PMC
abstract	OBJECTIVE: To delineate the clinical profile, complications, intensive care needs, and predictors of mortality in children with critical pertussis. METHODS: Retrospective analysis of case records of children in the pediatric intensive care unit of a tertiary-care hospital, with a diagnosis of critical pertussis over 3 years. Diagnostic criteria included CDC case definition and confirmation by polymerase chain reaction (PCR), when available. Survivors and nonsurvivors were compared to identify predictors of mortality. RESULTS: 36 records were analysed, most cases were infants (31, 86.1%). 10 (27.7%) were (below 6 weeks of age). In the rest, 16 (61.5%) were partially immunized or unimmunized against pertussis. Rapid breathing (88.9%), paroxysmal cough (86.1%) and apnea (41.7%) were common presenting complaints. Hypoxemia (97.2%), hyperleukocytosis (61.1%) and encephalopathy (52.8%) were common complications. Intensive care needs were mechanical ventilation in 11 (30.6%), vasoactive support in 7 (19.4%) and exchange transfusion in 3 (8.3%). Female gender, apnea, hyperleukocytosis, encephalopathy, need for vasoactive support, and mechanical ventilation predicted mortality. CONCLUSION: Pertussis demands attention due to its varied presentation, increased complications and higher mortality.
has issue date	2020-03-30(xsd:dateTime)
bibo:doi	10.1007/s13312-020-1756-3
bibo:pmid	32198862
has license	no-cc
sha1sum (hex)	eb6b57d726b77c98a98a53e9d38f2d6ce1f26e50
schema:url	https://doi.org/10.1007/s13312-020-1756-3
resource representing a document's title	Clinical Profile of Critical Pertussis in Children at a Pediatric Intensive Care Unit in Northern India
has PubMed Central identifier	PMC7223409
has PubMed identifier	32198862
schema:publication	Indian Pediatr
resource representing a document's body	covid:eb6b57d726b77c98a98a53e9d38f2d6ce1f26e50#body_text
is schema:about of	named entity 'presentation' named entity 'presenting' named entity 'Survivors' named entity 'case definition' named entity 'critical' named entity 'complications' named entity 'CDC' named entity 'SURVIVORS' named entity 'CHILDREN' named entity 'CONCLUSION' named entity 'records' named entity 'CDC' named entity 'support' named entity 'encephalopathy' named entity 'diagnosis' named entity 'Hypoxemia' named entity 'immunized' named entity 'exchange transfusion' named entity 'vasoactive' named entity 'complications' named entity 'apnea' named entity 'Intensive care' named entity 'encephalopathy' named entity 'mechanical ventilation' named entity 'unimmunized' named entity 'pertussis' named entity 'Northern India' named entity 'apnoea' named entity 'pertussis' named entity 'secondary infection' named entity 'exchange transfusion' named entity 'ICU' named entity 'mechanical ventilation' named entity 'PERTUSSIS' named entity 'ICU' named entity 'apneic' named entity 'conventional ventilation' named entity 'PAH' named entity 'vaccine' named entity 'PAH' named entity 'vomiting' named entity 'acute respiratory infection' named entity 'PCR' named entity 'Prospective studies' named entity 'ventilator-associated pneumonia' named entity 'maternal immunization' named entity 'pertussis' named entity 'leukocyte count' named entity 'intubation' named entity 'hypoxemia' named entity 'immunization' named entity 'unimmunized' named entity 'univariate analysis' named entity 'cough' named entity 'pertussis' named entity 'pertussis' named entity 'vaccination' named entity 'bacteria' named entity 'exchange transfusion' named entity 'intubated' named entity 'PAH' named entity 'mechanical ventilation' named entity 'PAH' named entity 'Intensive care' named entity 'Exchange transfusion' named entity 'middle-income' named entity 'lymphocytes' named entity 'life-threatening' named entity 'WHO' named entity 'intubation' named entity 'pertussis' named entity '1.1' named entity 'PCR' named entity 'preventable disease' named entity 'pertussis' named entity 'pertussis' named entity 'Pulmonary arterial'

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