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About:
Influenza treatment with neuraminidase inhibitors: Cost-effectiveness and cost-utility in healthy adults in the United Kingdom
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covidontheweb.inria.fr
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Type:
Academic Article
research paper
schema:ScholarlyArticle
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type
Academic Article
research paper
schema:ScholarlyArticle
isDefinedBy
Covid-on-the-Web dataset
has title
Influenza treatment with neuraminidase inhibitors: Cost-effectiveness and cost-utility in healthy adults in the United Kingdom
Creator
Sander, Beate
Er, Fred
Gic, Strate
Hay Den, G
Hoff Mann-, F
Ing, Pric
James, ·
Mann, Berge
Mar, ·
Mark, Gyld
Phar, Ltd
Ra Mueller, Elvi
Ris, Mor
Rito, ·
Roche, La
Vi, Di
Source
PMC
abstract
We assessed the cost-effectiveness and cost-utility of treating influenza with neuraminidase inhibitors (oseltamivir and zanamivir) from a health care payer’s and societal perspective in the United Kingdom. A simulation model was developed to predict morbidity and mortality due to influenza and its specified complications, comparing neuraminidase inhibitors with usual care in an otherwise healthy adult population. Robustness of the results was tested by one-way and multiway as well as probabilistic sensitivity analyses. Treatment with either neuraminidase inhibitor results in reduced morbidity and faster return to normal activities. However, oseltamivir dominates zanamivir in cost-utility analysis due to its lower costs. Comparing oseltamivir with usual care, the costs are £14.36 per day of normal activity gained and £5,600 per quality-adjusted life-year gained from the healthcare payer perspective. Oseltamivir dominates usual care from the societal perspective. Treatment with oseltamivir is a cost-effective strategy for otherwise healthy adults in the UK from both the healthcare payer and societal perspective.
has issue date
2005-09-17
(
xsd:dateTime
)
bibo:doi
10.1007/s10198-005-0297-y
bibo:pmid
15875227
has license
no-cc
sha1sum (hex)
e9cbd7607bbe38068fba47fb43fa6b3d3f854dce
schema:url
https://doi.org/10.1007/s10198-005-0297-y
resource representing a document's title
Influenza treatment with neuraminidase inhibitors: Cost-effectiveness and cost-utility in healthy adults in the United Kingdom
has PubMed Central identifier
PMC7087894
has PubMed identifier
15875227
schema:publication
Eur J Health Econ
resource representing a document's body
covid:e9cbd7607bbe38068fba47fb43fa6b3d3f854dce#body_text
is
schema:about
of
named entity 'PEO'
named entity 'AGED'
named entity 'ADULTS'
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named entity 'avail'
named entity 'ed King'
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named entity 'zanamivir'
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named entity 'ison'
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named entity 'NHS'
named entity 'zanamivir'
named entity 'zanamivir'
named entity 'zanamivir'
named entity 'zanamivir'
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