About: COVID-19, Hipertensión y Enfermedad cardiovascular

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About: COVID-19, Hipertensión y Enfermedad cardiovascular Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	COVID-19, Hipertensión y Enfermedad cardiovascular
Creator	Ennis, Irene Barochiner, Jessica Espeche, Walter Salazar, Martín
Source	Elsevier; Medline; PMC
abstract	Resumen La asociación entre patología cardiovascular y mala evolución de la infección por SARS-CoV-2 resulta llamativa. Estudios publicados en diferentes países muestran que la hipertensión, diabetes, enfermedad cerebrovascular y cardiopatía isquémica son marcadamente más frecuentes en aquellos pacientes que requieren cuidados críticos o fallecen por COVID-19. Un posible nexo causal sería el daño y disfunción miocárdica producidos por el SARS-CoV-2, evidenciado en los frecuentes hallazgos de elevación de la troponina y anormalidades electrocardiográficas. Por otra parte, existen hipótesis a favor y en contra de un posible efecto deletéreo de los inhibidores de la enzima convertidora y los bloqueantes del receptor de angiotensina 2 en esta patología, no habiendo actualmente evidencia sólida que respalde contundentemente una u otra, resultando impostergable la necesidad de estudios que diluciden este interrogante. Los pacientes con enfermedad cardiovascular deberían evitar especialmente la exposición al SARS-CoV-2, no automedicarse y consultar rápidamente ante la aparición de síntomas. Abstract The association between hypertension, diabetes, cardio and cerebrovascular disease and severe and fatal COVID-19, described in different countries, is remarkable. Myocardial damage and myocardial dysfunction are postulated as a possible causal nexus. Frequent findings of elevated troponin levels and electrocardiographic anomalies support this concept. On the other hand, hypotheses in favour and against a deleterious effect of angiotensin converting enzyme inhibitors and angiotensin receptor blockers, a usual treatment for cardiovascular disease, have been raised. There is currently no solid evidence and thus properly designed studies on this subject are urgently needed. In this context, patients with cardiovascular disease should especially avoid being exposed to the virus, should not self-medicate and rapidly seek medical advice should they show symptoms of infection.
has issue date	2020-06-18(xsd:dateTime)
bibo:doi	10.1016/j.hipert.2020.06.003
bibo:pmid	32591283
has license	els-covid
sha1sum (hex)	e72191d68253df58459934440cebafd14c514f43
schema:url	https://doi.org/10.1016/j.hipert.2020.06.003
resource representing a document's title	COVID-19, Hipertensión y Enfermedad cardiovascular
has PubMed Central identifier	PMC7301092
has PubMed identifier	32591283
schema:publication	Hipertens Riesgo Vasc
resource representing a document's body	covid:e72191d68253df58459934440cebafd14c514f43#body_text
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