About: Enterovirus D68 respiratory infection in a children's hospital in Japan in 2015

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Enterovirus D68 respiratory infection in a children's hospital in Japan in 2015 Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Enterovirus D68 respiratory infection in a children's hospital in Japan in 2015
Creator	Shimizu, Hiroyuki Fujimoto, Tsuguto Hanaoka, Nozomu Konagaya, Masami Doan, Yen Morino, Saeko Akiba, Tetsuya Chiba, Takashi Funakoshi, Yu Horikoshi, Yuho Ito, Kenta Kinoshita, Kazue Kono, Tatsuo Morikawa, Yoshihiko Shimizu, Norio Suzuki, Ai Tomaru, Yasuhiro Watanabe, Ken
Source	Medline; PMC
abstract	BACKGROUND: Outbreaks of enterovirus D68 (EV‐D68) respiratory infections in children were reported globally in 2014. In Japan, there was an EV‐D68 outbreak in the autumn of 2015 (September–October). The aim of this study was to compare EV‐D68‐specific polymerase chain reaction (PCR)‐positive and EV‐D68‐specific PCR‐negative patients. METHODS: Pediatric patients admitted for any respiratory symptoms between September and October 2015 were enrolled. Nasopharyngeal swabs were tested for multiplex respiratory virus PCR and EV‐D68‐specific reverse transcription‐PCR. EV‐D68‐specific PCR‐positive and ‐negative patients were compared regarding demographic data and clinical information. RESULTS: A nasopharyngeal swab was obtained from 76 of 165 patients admitted with respiratory symptoms during the study period. EV‐D68 was detected in 40 samples (52.6%). Median age in the EV‐D68‐specific PCR‐positive and ‐negative groups was 3.0 years (IQR, 5.5 years) and 3.0 years (IQR, 4.0 years), respectively. The rates of coinfection in the two groups were 32.5% and 47.2%, respectively. There was no significant difference in the history of asthma or recurrent wheezing, length of hospitalization, or pediatric intensive care unit admission rate between the groups. The median days between symptom onset and admission was significantly lower for the EV‐D68‐positive group (3.0 days vs 5.0 days, P = 0.001). EV‐D68 was identified as clade B on phylogenetic analysis. No cases of acute flaccid myelitis were encountered. CONCLUSIONS: More than half of the samples from the children admitted with respiratory symptoms were positive for EV‐D68‐specific PCR during the outbreak. Asthma history was not associated with the risk of developing severe respiratory infection.
has issue date	2019-08-22(xsd:dateTime)
bibo:doi	10.1111/ped.13903
bibo:pmid	31136073
has license	no-cc
sha1sum (hex)	e6ad7c4a14a996eabdd0bf183ffde0bd9c70249d
schema:url	https://doi.org/10.1111/ped.13903
resource representing a document's title	Enterovirus D68 respiratory infection in a children's hospital in Japan in 2015
has PubMed Central identifier	PMC7167638
has PubMed identifier	31136073
schema:publication	Pediatr Int
resource representing a document's body	covid:e6ad7c4a14a996eabdd0bf183ffde0bd9c70249d#body_text
is schema:about of	named entity 'patients' named entity 'PCR' named entity 'respiratory' named entity 'PCR' named entity 'length' named entity '2015' named entity 'EV-D68' named entity 'days' named entity 'EV-D68' named entity 'clade' named entity 'respiratory' named entity 'Enterovirus D68' named entity 'ACUTE FLACCID MYELITIS' named entity 'SPECIFIC' named entity 'SEPTEMBER' named entity 'NO CASES' named entity 'MORE THAN' named entity 'PCR' named entity 'COINFECTION' named entity '5.5' named entity 'LOWER' named entity 'JAPAN' named entity 'SAMPLES' named entity 'More' named entity 'EV-D68' named entity 'symptoms' named entity 'patients' named entity 'Asthma' named entity 'EV-D68' named entity 'Results' named entity 'detected' named entity 'aim' named entity 'outbreak' named entity 'groups' named entity 'EV-D68' named entity 'Nasopharyngeal swabs' named entity 'EV-D68' named entity 'Pediatric patients' named entity 'respiratory symptoms' named entity 'Japan' named entity 'significant difference' named entity 'pediatric intensive care unit' named entity '5.5' named entity 'children's hospital' named entity 'PCR' named entity 'RSV' named entity 'polymerase chain reaction' named entity 'respiratory infection' named entity 'EV-D68' named entity 'wheezing' named entity 'lung' named entity 'EV-D68' named entity 'respiratory syncytial viruses' named entity 'RT-PCR' named entity 'respiratory infections' named entity 'pediatric intensive care unit' named entity 'pediatric' named entity 'ICU' named entity 'nested RT-PCR' named entity 'selection bias' named entity 'PCR' named entity 'EV-D68' named entity 'asthma' named entity 'respiratory illness'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software