About: An Experimental Model for Dilated Cardiomyopathy after Rabbit Coronavirus Infection

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	An Experimental Model for Dilated Cardiomyopathy after Rabbit Coronavirus Infection
Creator	Baric, Ralph Small, J Alexander, Lorraine Edwards, Suzanne
Source	Medline; PMC
abstract	A rabbit model for coronavirus-induced dilated cardiomyopathy is described. Acute rabbit coronavirus infection results in virus-induced myocarditis and congestive heart failure. Of the survivors of rabbit coronavirus infection, 41% had increased heart weight and heart weight-to-body weight ratios, biventricular dilation, myocyte hypertrophy, myocardial fibrosis, and myocarditis consistent with the development of dilated cardiomyopathy. These changes were also seen in the remaining 59% of the survivors, except that the degree of myocyte hypertrophy was reduced and only right ventricular dilation was present. In most survivors, myocarditis was usually mild (1–5 foci/transverse section), but in some cases it was severe (>20 foci/transverse section). Interstitial and replacement fibrosis was more pronounced in the papillary muscles. These data suggest that rabbit coronavirus infection may progress to dilated cardiomyopathy.
has issue date	1992-11-01(xsd:dateTime)
bibo:doi	10.1093/infdis/166.5.978
bibo:pmid	1328411
has license	no-cc
sha1sum (hex)	e33f87cd7ac536211c69feeeaaff2e9c8077538c
schema:url	https://doi.org/10.1093/infdis/166.5.978
resource representing a document's title	An Experimental Model for Dilated Cardiomyopathy after Rabbit Coronavirus Infection
has PubMed Central identifier	PMC7109931
has PubMed identifier	1328411
schema:publication	J Infect Dis
resource representing a document's body	covid:e33f87cd7ac536211c69feeeaaff2e9c8077538c#body_text
is schema:about of	named entity 'data' named entity 'myocarditis' named entity 'congestive heart failure' named entity 'Rabbit' named entity 'DILATED CARDIOMYOPATHY' named entity 'FIBROSIS' named entity 'FOCI' named entity 'BIVENTRICULAR DILATION' named entity 'PROGRESS' named entity 'MYOCARDITIS' named entity 'MILD' named entity 'SECTION' named entity 'DEVELOPMENT' named entity 'EXCEPT' named entity 'DILATED CARDIOMYOPATHY' named entity 'RIGHT VENTRICULAR DILATION' named entity 'VIRUS' named entity 'RABBIT MODEL' named entity 'DATA' named entity 'SUGGEST' named entity 'REDUCED' named entity 'REPLACEMENT' named entity 'USUALLY' named entity 'INDUCED' named entity 'RATIOS' named entity 'THESE' named entity 'CORONAVIRUS' named entity 'MYOCARDIAL FIBROSIS' named entity 'PAPILLARY MUSCLES' named entity 'PRESENT' named entity 'CHANGES' named entity 'SEVERE' named entity 'EXPERIMENTAL MODEL' named entity 'CORONAVIRUS INFECTION' named entity 'RABBIT CORONAVIRUS' named entity 'ACUTE' named entity 'CONSISTENT WITH' named entity 'CASES' named entity 'HEART WEIGHT' named entity 'INCREASED HEART WEIGHT' named entity 'REMAINING' named entity 'WEIGHT' named entity 'RESULTS' named entity 'MYOCYTE HYPERTROPHY' named entity 'DEGREE' named entity 'SURVIVORS' named entity 'DESCRIBED' named entity 'CORONAVIRUS INFECTION' named entity 'RABBIT CORONAVIRUS' named entity 'INTERSTITIAL' named entity 'BUT' named entity 'SEEN' named entity 'CONGESTIVE HEART FAILURE' covid:arg/e33f87cd7ac536211c69feeeaaff2e9c8077538c named entity 'Acute' named entity 'infection' named entity 'foci' named entity 'biventricular' named entity 'infection' named entity 'dilated cardiomyopathy' named entity 'mild' named entity 'consistent' named entity 'Dilated Cardiomyopathy' named entity 'fibrosis' named entity 'coronavirus' named entity 'coronavirus' named entity 'myocardial fibrosis' named entity 'increased heart weight' named entity 'dilated cardiomyopathy' named entity 'coronavirus' named entity 'infection' named entity 'myocarditis' named entity 'hypertrophy' named entity 'myocarditis' named entity 'Interstitial' named entity 'hypertrophy' named entity 'hypertrophy' named entity 'DCM'

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