About: Effects of oropharyngeal administration of colostrum on the incidence of necrotizing enterocolitis, late-onset sepsis, and death in preterm infants: a meta-analysis of RCTs

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Effects of oropharyngeal administration of colostrum on the incidence of necrotizing enterocolitis, late-onset sepsis, and death in preterm infants: a meta-analysis of RCTs Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Effects of oropharyngeal administration of colostrum on the incidence of necrotizing enterocolitis, late-onset sepsis, and death in preterm infants: a meta-analysis of RCTs
Creator	Mao, Jing Su, Yanwei Tao, Jiaxin Yang, Jixin
Source	PMC
abstract	Necrotizing enterocolitis (NEC) and late-onset sepsis (LOS) are two major contributors to death among preterm infants. Oropharyngeal administration of colostrum (OAC) has been proved as an easy, safe, and economically viable technique to help preterm neonates to build up their immunity. In this review, we assessed the effects of OAC on preterm infants. Several mainstream databases were searched including PubMed, EMBASE, Cochrane Central Register of Controlled Trials (CENTRAL), and a website of clinical trials. Randomized controlled trials (RCTs) comparing OAC vs. placebo or no intervention in preterm infants (gestation age <34 weeks or birth weight <1500 g) were eligible. Overall, nine RCTs (n = 689) were included in the review. Meta-analysis showed no statistical significance in terms of the incidence of NEC (RR = 0.59, 95% CI = 0.33–1.06, p = 0.08), LOS (RR = 0.78, 95% CI = 0.60–1.03, p = 0.08) and mortality rate (RR = 0.63, 95% CI = 0.38–1.05, p = 0.07). No significant difference was found in the subgroup analysis, apart from the group of the undeveloped region in NEC and mortality. In addition, time was significantly reduced in terms of achieving full enteral feeding (MD = −3.60, 95% CI = −6.55–0.64, p = 0.02) and hospital stay (MD = −10.38, 95% CI = −18.47–2.29, p = 0.01). The results show that OAC does not reduce the incidences of NEC, LOS, and death in preterm infants, but there is a trend toward a positive effect. It is therefore recommended as routine care for preterm infants in the NICU.
has issue date	2020-01-03(xsd:dateTime)
bibo:doi	10.1038/s41430-019-0552-4
bibo:pmid	31901083
has license	no-cc
sha1sum (hex)	e279e7ca3a3617b831928ad657401d783d38ca07
schema:url	https://doi.org/10.1038/s41430-019-0552-4
resource representing a document's title	Effects of oropharyngeal administration of colostrum on the incidence of necrotizing enterocolitis, late-onset sepsis, and death in preterm infants: a meta-analysis of RCTs
has PubMed Central identifier	PMC7222151
has PubMed identifier	31901083
schema:publication	Eur J Clin Nutr
resource representing a document's body	covid:e279e7ca3a3617b831928ad657401d783d38ca07#body_text
is schema:about of	named entity 'stay' named entity 'Randomized controlled trials' named entity 'terms' named entity 'LOS' named entity 'viable' named entity 'preterm' named entity 'sepsis' named entity 'infants' named entity 'INCLUDING' named entity '0.64' named entity 'CLINICAL TRIALS' named entity 'COMPARING' named entity 'SAFE' named entity 'WEBSITE' named entity 'RANDOMIZED CONTROLLED TRIALS' named entity 'MORTALITY RATE' named entity 'ONSET' named entity 'ENTERAL FEEDING' named entity 'STATISTICAL SIGNIFICANCE' named entity 'infants' named entity 'EMBASE' named entity 'addition' named entity 'infants' named entity 'hospital' named entity 'reduced' named entity 'OAC' named entity 'Meta-analysis' named entity 'preterm' named entity 'Trials' named entity 'statistical significance' named entity 'colostrum' named entity 'European' named entity 'NEC' named entity 'birth weight' named entity 'Necrotizing enterocolitis' named entity 'significant difference' named entity 'NEC' named entity 'NICU' named entity 'Randomized controlled trials' named entity 'NEC' named entity 'colostrum' named entity 'European Journal of Clinical Nutrition' named entity 'preterm' named entity '95% CI' named entity 'control group' named entity 'inclusion and exclusion criteria' named entity 'NEC' named entity 'colostrum' named entity 'statistical significance' named entity 'lymphocytes' named entity 'preterm infants' named entity 'lactoferrin' named entity 'milk' named entity 'pneumonia' named entity 'NEC' named entity 'oropharyngeal' named entity 'double-blind' named entity 'NEC' named entity 'NEC' named entity 'RCT' named entity 'preterm infants' named entity 'active substances' named entity 'blood culture' named entity 'NEC' named entity 'modern medicine' named entity 'systemic review' named entity 'premature infant' named entity 'preterm neonates' named entity 'control group' named entity 'control group' named entity 'long-term' named entity 'medical condition' named entity 'amino acid' named entity 'statistical significance' named entity 'sample size' named entity 'sepsis' named entity 'oropharyngeal' named entity 'NICU'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software