About: Human metapneumovirus genotypes and severity of disease in young children (n = 100) during a 7‐year study in Dijon hospital, France

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About: Human metapneumovirus genotypes and severity of disease in young children (n = 100) during a 7‐year study in Dijon hospital, France Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Human metapneumovirus genotypes and severity of disease in young children (n = 100) during a 7‐year study in Dijon hospital, France
Creator	Pothier, Pierre Manoha, Catherine Aho, Serge-Ludwig Cile Pitoiset, Cé Darniot, Magali Dé Ric Huet, Fré
source	Medline; PMC
abstract	Human metapneumovirus is a cause of respiratory tract infections at all ages. Our objectives were to analyze the distribution of the A and B genotypes over 7 years in Dijon and to investigate a possible association between hMPV genotypes and disease severity. During 2002–2009, we genotyped the 100 isolates from children <3 years old with hMPV. Phylogenetic analysis indicated a change in the distribution of hMPV genotype over the years. Severity was then measured by detailed clinical evaluation. The hospitalization rate was greater when genotype B was involved 72.5% versus 53.3% (P = 0.054). Those infected with genotype B tended to have a higher clinical score, as measured by Vicente et al. 2006 (P = 0.07). We showed that, although clinical severity is not clearly associated with hMPV genotype in this study, pathological signs on chest X‐ray were observed more often in B subgroup (P < 0.01). J. Med. Virol. 82:1782–1789, 2010. © 2010 Wiley‐Liss, Inc.
has issue date	2010-09-01(xsd:dateTime)
bibo:doi	10.1002/jmv.21884
bibo:pmid	20827777
has license	no-cc
sha1sum (hex)	e1895ec2cdc422394f8d20d542f598e7de461d8c
schema:url	https://doi.org/10.1002/jmv.21884
resource representing a document's title	Human metapneumovirus genotypes and severity of disease in young children (n = 100) during a 7‐year study in Dijon hospital, France
has PubMed Central identifier	PMC7166491
has PubMed identifier	20827777
schema:publication	J Med Virol
resource representing a document's body	covid:e1895ec2cdc422394f8d20d542f598e7de461d8c#body_text
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