About: Validation of a novel severe acute respiratory syndrome scoring system

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Validation of a novel severe acute respiratory syndrome scoring system
Creator	Chen, Shey-Ying Chen, Wen-Jone Chiang, Wen-Chu Su, Chan-Ping Chang, Shan-Chwen Chen, Shyr-Chyr Chen, Yee-Chun Hsu, Chiung-Yuan Ko, Patrick Chow-In Shih, Fuh-Yuan Tsai, Kuang-Chau Fan, Chieh-Min Huei, Matthew Ma, Ming
Source	Elsevier; Medline; PMC
abstract	Abstract Study objective In a pilot study conducted during March 14 to April 2, 2003, 2 severe acute respiratory syndrome (SARS) screening scores were developed for predicting SARS among febrile patients presenting to the emergency department (ED). The objective of this study is to validate these scoring systems with a different set of patients. Methods All adult patients with documented fever, measured at home or at the hospital, and presenting to the ED of National Taiwan University Hospital, a 2,400-bed tertiary care teaching hospital in northern Taiwan, were prospectively enrolled. Two previously developed SARS screening scores were applied to all patients. The final diagnosis of SARS was made by the Expert Committee of the Center for Disease Control Taiwan, Republic of China, according to the criteria of Centers for Disease Control and Prevention, Atlanta, GA. Results A total of 239 adult patients, including 117 men and 122 women, were enrolled. Eighty-two patients were finally diagnosed with SARS. Compared with the SARS patients in the derivation cohort, those in the validation cohort were older (44.5±15.9 versus 33.9±15.9 years), more likely to acquire the disease locally (76.8% versus 37.5%), and more likely to have cough before or during fever. For the non-SARS patients, cases in the validation cohort presented with less cough and coryza but more diarrhea. For the 4-item symptom score, the sensitivity reached 96.3% (95% confidence interval [CI] 89.7% to 98.7%) and the specificity 51.6% (95% CI 43.8% to 59.3%). For the 6-item clinical score, the sensitivity reached 92.6% (95% CI 84.8% to 96.6%) and the specificity 71.2% (95% CI 63.6% to 77.7%). When the clinical score was applied to patients with a positive symptom score, the combined sensitivity reached 90.2% (95% CI 82.0% to 95.0%), and the combined specificity reached 80.1% (95% CI 73.2% to 85.6%). Conclusion This prospective study validated the scoring system previously developed by using a different cohort. The scoring systems could be applied to settings where mass screening of SARS is needed during future outbreaks.
has issue date	2004-01-31(xsd:dateTime)
bibo:doi	10.1016/j.annemergmed.2003.10.042
bibo:pmid	14707938
has license	els-covid
sha1sum (hex)	e059b3b0ef08f641376033ff68ad37b61bdd5cc8
schema:url	https://doi.org/10.1016/j.annemergmed.2003.10.042
resource representing a document's title	Validation of a novel severe acute respiratory syndrome scoring system
has PubMed Central identifier	PMC7124226
has PubMed identifier	14707938
schema:publication	Annals of Emergency Medicine
resource representing a document's body	covid:e059b3b0ef08f641376033ff68ad37b61bdd5cc8#body_text
is schema:about of	named entity 'SEVERE ACUTE RESPIRATORY SYNDROME' named entity 'System' named entity 'A N' named entity 'L S' named entity 'SCORING SYSTEM' named entity 'D I' named entity 'VALIDATION' named entity 'R C' named entity 'NOVEL' named entity 'D I C' named entity 'U S' named entity '95% CI' named entity 'leukopenia' named entity 'sore throat' named entity 'National Taiwan University Hospital' named entity 'Taiwan' named entity 'symptom' named entity 'Student's t test' named entity 'early diagnosis' named entity 'absolute lymphocyte count' named entity 'symptom' named entity 'SARS' named entity '95% CI' named entity 'SARS' named entity 'febrile' named entity 'SPSS' named entity 'pneumonia' named entity 'febrile' named entity 'symptom' named entity '4.14' named entity 'National Taiwan University Hospital' named entity 'SARS' named entity 'laboratory tests' named entity 'health care' named entity 'laboratory tests' named entity 'medical record' named entity 'epidemiologic' named entity 'febrile' named entity 'SARS' named entity 'SARS' named entity 'Taiwan' named entity 'SARS' named entity 'radiographic' named entity 'SARS' named entity 'endemic' named entity 'Lymphopenia' named entity 'SARS' named entity 'false positive and false negative' named entity 'MHMM' named entity 'underlying diseases' named entity 'epidemic' named entity 'observational study' named entity 'SARS' named entity 'fever' named entity 'quarantine' named entity 'positive predictor' named entity 'SARS' named entity 'cough' named entity 'SARS' named entity 'sensitivity, specificity' named entity '36,000 km' named entity 'Hong Kong' named entity '95% CI' named entity 'positive symptom' named entity 'MHMM' named entity 'WHO' named entity 'chest radiograph' named entity 'April 24'

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