About: Genomic epidemiology of the early stages of SARS-CoV-2 outbreak in Russia

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Genomic epidemiology of the early stages of SARS-CoV-2 outbreak in Russia
Creator	Fadeev, Artem Komissarov, Andrey Bazykin, Georgii Danilenko, Daria Garushyants, Sofya Glyzin, Dmitry Ivanova, Anna Lioznov, Dmitry Safina, Ksenia Sergeeva, Mariia Shchur, Vladimir Shneider, Olga Shvyrev, Nikita Spirin, Vadim
Source	MedRxiv
abstract	The ongoing pandemic of SARS-CoV-2 presents novel challenges and opportunities for the use of phylogenetics to understand and control its spread. Here, we analyze the emergence of SARS-CoV-2 in Russia in March and April 2020. Combining phylogeographic analysis with travel history data, we estimate that the sampled viral diversity has originated from 67 closely timed introductions into Russia, mostly in late February to early March. All but one of these introductions came from non-Chinese sources, suggesting that border closure with China has helped delay establishment of SARS-CoV-2 in Russia. These introductions resulted in at least 9 distinct Russian lineages corresponding to domestic transmission. A notable transmission cluster corresponded to a nosocomial outbreak at the Vreden hospital in Saint Petersburg; phylodynamic analysis of this cluster reveals multiple (2-4) introductions each giving rise to a large number of cases, with a high initial effective reproduction number of 3.7 (2.5-5.0).
has issue date	2020-07-17(xsd:dateTime)
bibo:doi	10.1101/2020.07.14.20150979
has license	medrxiv
sha1sum (hex)	dfeed3352a15f3770efc3709a2479274481d731f
schema:url	https://doi.org/10.1101/2020.07.14.20150979
resource representing a document's title	Genomic epidemiology of the early stages of SARS-CoV-2 outbreak in Russia
resource representing a document's body	covid:dfeed3352a15f3770efc3709a2479274481d731f#body_text
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