About: Poor-sleep is associated with slow recovery from lymphopenia and an increased need for ICU care in hospitalized patients with COVID-19: A retrospective cohort study

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Poor-sleep is associated with slow recovery from lymphopenia and an increased need for ICU care in hospitalized patients with COVID-19: A retrospective cohort study Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Poor-sleep is associated with slow recovery from lymphopenia and an increased need for ICU care in hospitalized patients with COVID-19: A retrospective cohort study
Creator	Liu, Hongmei Xu, Dan Chen, H Zhang, J Yuan, S Shang, You Yuan, Shiying Hashimoto, Kenji Huang, H Huang, Haiyan Liu, H Xu, D Zhang, Y Sun, Y Hashimoto, K Xie, Bing Zhang, Jiancheng Zhang, Yujing Chen, Huaqi Shang, Y Sun, Yongbo
topic	covid:df99f9c1da4ba098b9d6a493d003713b4f7e1355#this
Source	Elsevier; Medline; PMC
abstract	Sleep is known to play an important role in immune function. However, the effects of sleep quality during hospitalization for COVID-19 remain unclear. This retrospective, single-center cohort study was conducted to investigate the effects of sleep quality on recovery from lymphopenia and clinical outcomes in hospitalized patients with laboratory-confirmed COVID-19 admitted to the West District of Wuhan Union Hospital between January 25 and March 15, 2020. The Richards-Campbell sleep questionnaire (RCSQ) and Pittsburgh Sleep Quality Index (PSQI) were used to assess sleep quality. The epidemiological, demographic, clinical, laboratory, treatment, and outcome data were collected from electronic medical records and compared between the good-sleep group and poor-sleep group. In all, 135 patients (60 in good-sleep group and 75 in poor-sleep group) were included in this study. There were no significant between-group differences regarding demographic and baseline characteristics, as well as laboratory parameters upon admission and in-hospital treatment. Compared with patients in the good-sleep group, patients in the poor-sleep group had lower absolute lymphocyte count (ALC) (day 14: median, 1.10 vs 1.32, P = 0.0055; day 21: median, 1.18 vs 1.48, P = 0.0034) and its reduced recovery rate (day 14: median, 56.91 vs 69.40, P = 0.0255; day 21: median, 61.40 vs 111.47, P = 0.0003), as well as increased neutrophil-to-lymphocyte ratio (NLR; day 14: median, 3.17 vs 2.44, P = 0.0284; day 21: median, 2.73 vs 2.23, P = 0.0092) and its associated deterioration rate (day 14: median, -39.65 vs -61.09, P = 0.0155; day 21: median, -51.40% vs -75.43, P = 0.0003). Nine [12.0%] patients in the poor-sleep group required ICU care (P = 0.0151); meanwhile, none of the patients in good-sleep group required ICU care. Patients in the poor-sleep group had increased duration of hospital stay (33.0 [23.0–47.0] days vs 25.0 [20.5–36.5] days, P = 0.0116) compared to those in the good-sleep group. An increased incidence of hospital-acquired infection (seven [9.3%] vs one [1.7%]) was observed in the poor-sleep group compared to the good-sleep group; however, this difference was not significant (P = 0.1316). In conclusion, poor sleep quality during hospitalization in COVID-19 patients with lymphopenia is associated with a slow recovery from lymphopenia and an increased need for ICU care.
has issue date	2020-06-06(xsd:dateTime)
bibo:doi	10.1016/j.bbi.2020.05.075
bibo:pmid	32512133
has license	no-cc
sha1sum (hex)	df99f9c1da4ba098b9d6a493d003713b4f7e1355
schema:url	https://doi.org/10.1016/j.bbi.2020.05.075
resource representing a document's title	Poor-sleep is associated with slow recovery from lymphopenia and an increased need for ICU care in hospitalized patients with COVID-19: A retrospective cohort study
has PubMed Central identifier	PMC7274970
has PubMed identifier	32512133
schema:publication	Brain Behav Immun
resource representing a document's body	covid:df99f9c1da4ba098b9d6a493d003713b4f7e1355#body_text
is http://vocab.deri.ie/void#inDataset of	proxy:http/ns.inria.fr/covid19/df99f9c1da4ba098b9d6a493d003713b4f7e1355
is schema:about of	named entity 'compared' named entity 'January 25' named entity 'hospitalized' named entity 'SLEEP' named entity 'REFERENCES' named entity 'SINGLE' named entity 'USED' named entity 'EPIDEMIOLOGICAL' named entity 'However' named entity 'Hospital' named entity 'collected' named entity 'Sleep' named entity 'immune function' named entity 'Legends' named entity 'effects' named entity 'data' named entity 'laboratory' named entity 'ICU' named entity 'sleep quality' named entity 'demographic' named entity 'sleep quality' named entity 'electronic medical records' named entity 'outcome data' named entity 'ICU' named entity 'lymphopenia' named entity 'COVID' named entity 'Kidney Disease' named entity 'Malignancy' named entity 'serum' named entity 'COVID' named entity 'homeostasis' named entity 'ICU' named entity 'vital signs' named entity 'body temperature' named entity 'oxygen therapy' named entity 'case series' named entity 'disrupted sleep' named entity 'HAI' named entity 'inflammation' named entity 'COVID' named entity 'upper respiratory infections' named entity 'PSQI' named entity 'Wuhan Union Hospital' named entity 'peripheral blood lymphocytes' named entity 'final analysis' named entity 'liver dysfunction' named entity 'physiological' named entity 'Signs and symptoms' named entity 'loss of consciousness' named entity 'sleep latency' named entity 'sleep quality' named entity 'ICU' named entity 'sleep quality' named entity 'COVID' named entity 'sleep quality' named entity 'peripheral blood lymphocytes' named entity 'Urologic' named entity 'sleep quality' named entity 'comorbidities'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software