About: Pathological Changes During Aging in, Barrier-Reared Fischer 344 Male Rats(1)

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Pathological Changes During Aging in, Barrier-Reared Fischer 344 Male Rats(1)
Creator	Jonas, Albert Barthold, Stephen Coleman, Gerald Foster, Sumner Osbaldiston, George
source	PMC
abstract	Pathology, microbiology, and selected serum chemistries were evaluated in 144 male Fischer rats from 4 to 33 mo of age. The rats were reared and maintained under barrier conditions, which successfully excluded the introduction of major infectious disease agents throughout the entire study, including Mycoplasma pulmonis. A wide variety of pathology was found and tabulated, and many lesions were found to increase in severity and incidence with age. There was a high correlation of renal disease severity with increasing age. Serum total protein and albumin decreased with age, while alpha-1 globulin and cholesterol increased.
has issue date	1977-05-01(xsd:dateTime)
bibo:doi	10.1093/geronj/32.3.258
bibo:pmid	66246
has license	no-cc
sha1sum (hex)	df35a500c54be0a3663a0ff820630e1aa2d72ac5
schema:url	https://doi.org/10.1093/geronj/32.3.258
resource representing a document's title	Pathological Changes During Aging in, Barrier-Reared Fischer 344 Male Rats(1)
has PubMed Central identifier	PMC7108513
has PubMed identifier	66246
schema:publication	J Gerontol
resource representing a document's body	covid:df35a500c54be0a3663a0ff820630e1aa2d72ac5#body_text
is schema:about of	named entity 'CONDITIONS' named entity 'INCLUDING' named entity 'INCREASED' named entity 'EVALUATED' named entity 'MYCOPLASMA PULMONIS' named entity 'RENAL DISEASE' named entity 'CHEMISTRIES' covid:arg/df35a500c54be0a3663a0ff820630e1aa2d72ac5 named entity 'hyperplasia' named entity 'splenomegaly' named entity 'tumor' named entity 'hepatotoxic' named entity 'erythrocytes' named entity 'mononuclear cell' named entity 'tumors' named entity 'thyroid' named entity 'bronchi' named entity 'infectious disease' named entity 'tumor' named entity 'pathology' named entity 'lesion' named entity 'periarteritis nodosa' named entity 'pathology' named entity 'tumor' named entity 'testicular atrophy' named entity 'Mycoplasma pulmonis' named entity 'correlation' named entity 'bile ducts' named entity 'seminal vesicles' named entity 'hepatic' named entity 'pigment' named entity 'reticulum cell sarcoma' named entity 'hyperplasia' named entity 'Telangiectasis' named entity 'phagocytic cells' named entity 'renal impairment' named entity 'lesion' named entity 'kidneys' named entity 'lung' named entity 'testicular atrophy' named entity 'Alveoli' named entity 'pancreas' named entity 'Mycoplasma pulmonis' named entity 'alpha-1 globulin' named entity 'hyperplasia' named entity 'sialoadenitis' named entity 'Cystitis' named entity 'synovitis' named entity 'mesothelioma' named entity 'kidney disease' named entity 'hyperplasia' named entity 'renal disease' named entity 'tumors' named entity 'Adrenal cortical' named entity 'lesion' named entity 'gamma globulin' named entity 'fatty change' named entity 'Tumor' named entity 'Wilmington, MA' named entity 'erythroid' named entity 'paresis' named entity 'lymph node' named entity 'brain stem' named entity 'metastases' named entity 'older age' named entity 'leukemia' named entity 'liver' named entity 'lipomas' named entity 'morphological' named entity 'chronic respiratory disease' named entity 'hyperplasia' named entity '2 rats' named entity 'Kaunitz' named entity 'Mycoplasma pulmonis' named entity 'renal disease' named entity 'gynecomastia' named entity 'lesion'

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