About: The burden of respiratory infections among older adults in long-term care: a systematic review

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	The burden of respiratory infections among older adults in long-term care: a systematic review
Creator	Bosco, Elliott Childs, Arielle Gravenstein, Stefan Mor, Vincent Moyo, Patience Joyce, Nina Mcconeghy, Kevin Van Aalst, Robertus Zullo, Andrew
Source	Medline; PMC
abstract	BACKGROUND: Respiratory infections among older adults in long-term care facilities (LTCFs) are a major global concern, yet a rigorous systematic synthesis of the literature on the burden of respiratory infections in the LTCF setting is lacking. To address the critical need for evidence regarding the global burden of respiratory infections in LTCFs, we assessed the burden of respiratory infections in LTCFs through a systematic review of the published literature. METHODS: We identified articles published between April 1964 and March 2019 through searches of PubMed (MEDLINE), EMBASE, and the Cochrane Library. Experimental and observational studies published in English that included adults aged ≥60 residing in LTCFs who were unvaccinated (to identify the natural infection burden), and that reported measures of occurrence for influenza, respiratory syncytial virus (RSV), or pneumonia were included. Disagreements about article inclusion were discussed and articles were included based on consensus. Data on study design, population, and findings were extracted from each article. Findings were synthesized qualitatively. RESULTS: A total of 1451 articles were screened for eligibility, 345 were selected for full-text review, and 26 were included. Study population mean ages ranged from 70.8 to 90.1 years. Three (12%) studies reported influenza estimates, 7 (27%) RSV, and 16 (62%) pneumonia. Eighteen (69%) studies reported incidence estimates, 7 (27%) prevalence estimates, and 1 (4%) both. Seven (27%) studies reported outbreaks. Respiratory infection incidence estimates ranged from 1.1 to 85.2% and prevalence estimates ranging from 1.4 to 55.8%. Influenza incidences ranged from 5.9 to 85.2%. RSV incidence proportions ranged from 1.1 to 13.5%. Pneumonia prevalence proportions ranged from 1.4 to 55.8% while incidence proportions ranged from 4.8 to 41.2%. CONCLUSIONS: The reported incidence and prevalence estimates of respiratory infections among older LTCF residents varied widely between published studies. The wide range of estimates offers little useful guidance for decision-making to decrease respiratory infection burden. Large, well-designed epidemiologic studies are therefore still necessary to credibly quantify the burden of respiratory infections among older adults in LTCFs, which will ultimately help inform future surveillance and intervention efforts. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s12877-019-1236-6) contains supplementary material, which is available to authorized users.
has issue date	2019-08-05(xsd:dateTime)
bibo:doi	10.1186/s12877-019-1236-6
bibo:pmid	31382895
has license	cc-by
sha1sum (hex)	dc55c16e1cfe2f794a9924f28d4b2c487316d4d2
schema:url	https://doi.org/10.1186/s12877-019-1236-6
resource representing a document's title	The burden of respiratory infections among older adults in long-term care: a systematic review
has PubMed Central identifier	PMC6683564
has PubMed identifier	31382895
schema:publication	BMC Geriatr
resource representing a document's body	covid:dc55c16e1cfe2f794a9924f28d4b2c487316d4d2#body_text
is schema:about of	named entity 'LONG-TERM CARE' named entity 'respiratory infections' named entity 'Respiratory infections' named entity 'burden' named entity 'older adults' named entity 'BURDEN' named entity 'CRITICAL' named entity 'BURDEN' named entity 'SYNTHESIS OF THE LITERATURE' named entity 'REVIEW OF' named entity 'SETTING' named entity 'GLOBAL' named entity 'FACILITIES' named entity 'PUBLISHED' named entity 'ADDRESS' named entity 'RESPIRATORY INFECTIONS' named entity 'LITERATURE' named entity 'ASSESSED' named entity 'LONG-TERM CARE' named entity 'BACKGROUND' named entity 'SYSTEMATIC REVIEW' named entity 'LACKING' named entity 'RESPIRATORY INFECTIONS' named entity 'A MAJOR' named entity 'EVIDENCE' named entity 'SYSTEMATIC REVIEW' named entity 'CONCERN' named entity 'NEED FOR' covid:arg/dc55c16e1cfe2f794a9924f28d4b2c487316d4d2 named entity 'critical' named entity 'burden' named entity 'Embase' named entity 'pneumonia' named entity 'culture medium' named entity 'epithelium' named entity 'pneumonia' named entity 'antiviral' named entity 'Cochrane Database of Systematic Reviews' named entity 'bacterial pneumonia' named entity 'burden' named entity 'address' named entity 'literature' named entity 'respiratory infections' named entity 'risk factors' named entity 'older adults' named entity 'Systematic Review' named entity 'risk factors' named entity 'inclusion and exclusion criteria' named entity 'respiratory infections' named entity 'respiratory infections' named entity 'etiology' named entity 'cohort studies' named entity 'influenza' named entity 'RSV' named entity 'etiology' named entity 'typical antipsychotic' named entity 'respiratory infections' named entity 'respiratory infections' named entity 'influenza' named entity 'chemoprophylaxis' named entity 'respiratory infections' named entity 'systematic literature review' named entity 'viral testing' named entity 'Embase' named entity 'pneumonia' named entity 'epidemiology' named entity 'Respiratory infections' named entity 'respiratory infections' named entity 'immunization' named entity 'pneumonia' named entity 'study design' named entity 'respiratory infection' named entity 'RSV'

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