About: Antimicrobial De-Escalation in the ICU: From Recommendations to Level of Evidence

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Antimicrobial De-Escalation in the ICU: From Recommendations to Level of Evidence Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Antimicrobial De-Escalation in the ICU: From Recommendations to Level of Evidence
Creator	De, J Alexis, Waele Ignacio, Einav Jan, Ines Leone, Martin-Loeches Sharon, Tabah
Source	PMC
abstract	Antimicrobial de-escalation (ADE) is a component of antimicrobial stewardship (AMS) aimed to reduce exposure to broad-spectrum antimicrobials. In the intensive care unit, ADE is a strong recommendation that is moderately applied in clinical practice. Following a systematic review of the literature, we assessed the studies identified on the topic which included one randomized controlled trial and 20 observational studies. The literature shows a low level of evidence, although observational studies suggested that this procedure is safe. The effects of ADE on the level of resistance of ecological systems and especially on the microbiota are unclear. The reviewers recommend de-escalating antimicrobial treatment in patients requiring long-term antibiotic therapy and considering de-escalation in short-term treatments. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s12325-020-01390-2) contains supplementary material, which is available to authorized users.
has issue date	2020-05-27(xsd:dateTime)
bibo:doi	10.1007/s12325-020-01390-2
has license	cc-by-nc
sha1sum (hex)	dc1064263f8fa4809e9bbca0e06f83a88717dbae
schema:url	https://doi.org/10.1007/s12325-020-01390-2
resource representing a document's title	Antimicrobial De-Escalation in the ICU: From Recommendations to Level of Evidence
has PubMed Central identifier	PMC7252418
schema:publication	Adv Ther
resource representing a document's body	covid:dc1064263f8fa4809e9bbca0e06f83a88717dbae#body_text
is schema:about of	named entity 'therapy' named entity 'assessed' named entity 'Evidence' named entity 'LOW LEVEL' named entity 'MODERATELY' named entity 'ANTIMICROBIAL TREATMENT' named entity 'COMPONENT' named entity 'LEVEL OF EVIDENCE' named entity 'ASSESSED' named entity 'RESISTANCE' named entity 'RECOMMENDATION' named entity 'ANTIMICROBIAL STEWARDSHIP' named entity 'suggested' named entity 'de-escalation' named entity 'effects' named entity 'intensive care unit' named entity 'imipenem' named entity 'ADE' named entity 'antimicrobial resistance' named entity 'antibiotics' named entity 'severe sepsis' named entity 'b-lactam' named entity 'antimicrobial' named entity 'human gut' named entity 'ADE' named entity 'odds ratio' named entity 'observational data' named entity 'ADE' named entity 'colistin' named entity 'observational studies' named entity 'antimicrobial stewardship' named entity 'imipenem' named entity 'Delphi' named entity 'antimicrobial resistance' named entity 'antibiotic therapy' named entity 'ADE' named entity 'sensitivity analysis' named entity 'pharmacodynamic' named entity 'ADE' named entity 'antimicrobial' named entity 'imipenem' named entity 'ADE' named entity 'human participants' named entity 'antimicrobial therapy' named entity 'RCT' named entity 'resistome' named entity 'ADE' named entity 'de-escalation' named entity 'paediatric' named entity 'ADE' named entity 'ADE' named entity 'septic shock' named entity 'relative risk' named entity 'ADE' named entity 'ADE' named entity 'primary endpoint' named entity 'excretion' named entity 'Antimicrobial' named entity 'risk factors' named entity 'antibiotics' named entity 'antibiotics' named entity 'English language' named entity 'observational studies' named entity 'antimicrobials' named entity 'de-escalation' named entity 'antibiotic' named entity 'microbiome' named entity 'antibiotics' named entity 'patients' named entity 'broad-spectrum' named entity 'randomized controlled trial' named entity 'AMS' named entity 'literature' named entity 'ICU' named entity 'antimicrobials' named entity 'de-escalation' named entity 'clinical practice' named entity 'broad-spectrum'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software