About: A retrospective review of tuberculosis exposure among health care workers in a tertiary hospital

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	A retrospective review of tuberculosis exposure among health care workers in a tertiary hospital
Creator	Lin, Moi Abim, Chlebicki Bien, Kue Chia, Gabriel Mph, Molly Piotr, Maciej Zhe, Shi
Source	Elsevier; Medline; PMC
abstract	Background We evaluated tuberculosis (TB) acquisition rate and risk factors among health care workers (HCWs) exposed to index TB patients. Methods We performed a retrospective cohort study on exposed HCWs from August 2016 to January 2018 at a tertiary hospital in Singapore. Demographic factors and TB exposure episodes per HCW were obtained. A modified Poisson regression model was used to identify factors associated with TB infection. Results A total of 32 TB exposure events occurred during the study period. A total of 881 HCWs with 1,536 exposure episodes were screened with QuantiFERON-TB Gold In-tube assay (QFT-GIT) at baseline and 8 weeks. A total of 129 (14.6%) HCWs had positive QFT-TB at baseline, whereas 22 (2.5%) HCWs had QFT-GIT conversion, with a latent TB infection (LTBI) rate of 1.14 cases per 100 exposure episodes per year. Foreign nationality, non-Chinese ethnicity, and age above 40 years were independently associated with baseline LTBI, whereas having >2 TB exposure episodes and working in internal medicine, medical subspecialties, and psychiatry wards were associated with QFT-GIT conversion. Discussion The QFT-GIT conversion rate among screened HCWs is low. Foreign HCWs with LTBI likely came from countries with higher TB transmission. Targeted prevention of repeated TB exposures can reduce QFT-GIT conversion. Conclusions The study results will guide TB contact tracing protocols in health care institutions.
has issue date	2019-12-02(xsd:dateTime)
bibo:doi	10.1016/j.ajic.2019.10.014
bibo:pmid	31806237
has license	els-covid
sha1sum (hex)	db1f2e3f0b16df42a30f5bbb6b7508127a05de1f
schema:url	https://doi.org/10.1016/j.ajic.2019.10.014
resource representing a document's title	A retrospective review of tuberculosis exposure among health care workers in a tertiary hospital
has PubMed Central identifier	PMC7132713
has PubMed identifier	31806237
schema:publication	Am J Infect Control
resource representing a document's body	covid:db1f2e3f0b16df42a30f5bbb6b7508127a05de1f#body_text
is schema:about of	named entity 'RETROSPECTIVE' named entity 'prevention' named entity 'exposed' named entity 'performed' named entity 'LTBI' named entity 'infection' named entity 'subspecialties' named entity 'age' named entity 'HEALTH CARE' named entity 'INFECTION' named entity '3E2' named entity 'QUANTIFERON-TB GOLD' named entity 'LIKELY' named entity 'RESULTS' named entity 'TB EXPOSURE' named entity 'PER YEAR' named entity '1.14' named entity 'FOREIGN' named entity 'REGRESSION MODEL' named entity 'PROTOCOLS' named entity 'CASES' named entity 'HOSPITAL' named entity 'INDEX' named entity 'POSITIVE' named entity 'RATE' named entity 'BACKGROUND' named entity 'YEARS' named entity 'PSYCHIATRY' covid:arg/db1f2e3f0b16df42a30f5bbb6b7508127a05de1f named entity 'REDUCE' named entity 'TUBERCULOSIS' named entity 'NATIONALITY' named entity 'ASSOCIATED WITH' named entity 'DEMOGRAPHIC FACTORS' named entity 'INSTITUTIONS' named entity '8 WEEKS' named entity 'CONTACT TRACING' named entity 'TUBERCULOSIS EXPOSURE' named entity 'REVIEW OF' named entity 'HOSPITAL' named entity 'WORKERS' named entity 'TERTIARY' named entity 'CAME' named entity 'LTBI' named entity 'METHODS' named entity 'HEALTH CARE' named entity 'CHINESE' named entity 'PERFORMED' named entity 'STUDY' named entity 'GIT' named entity 'EXPOSURE' named entity 'ASSAY' named entity 'EVENTS' named entity 'OBTAINED' named entity '282' named entity 'WORKERS' named entity 'TERTIARY' named entity 'POISSON REGRESSION' named entity 'TRANSMISSION' named entity 'MODIFIED' named entity 'ACQUISITION RATE' named entity 'REPEATED' named entity 'CONCLUSIONS' named entity 'NON-' named entity 'EPISODES' named entity 'ETHNICITY' named entity 'BASELINE' named entity 'HIGHER' named entity 'TOTAL' named entity 'DISCUSSION' named entity 'USED' named entity 'TUBE' named entity 'RISK FACTORS' named entity 'PREVENTION OF' named entity 'MEDICAL'

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