About: Abstract Group A Streptococcus (GAS) or Streptococcus pyogenes, affects an estimated 800 million people each year. Most of the resulting estimated 639,000 annual deaths are related to rheumatic heart disease (RHD) and its complications. Resource-limited areas account for the vast majority of cases, although outbreaks still occur in industrialized countries. GAS has several mechanisms to avoid phagocytosis, including prevention of opsonization and the use of surface proteins to block complement fixation. The mechanisms behind the immunologic phenomenon are not well understood. Clinical presentations range from benign, short-lived impetigo or pharyngitis through to lifelong RHD. In its most invasive form, GAS can cause a rapidly progressive, often lethal infection: streptococcal toxic shock syndrome. S. pyogenes remains universally sensitive to penicillin, which is the mainstay of treatment.

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About: Abstract Group A Streptococcus (GAS) or Streptococcus pyogenes, affects an estimated 800 million people each year. Most of the resulting estimated 639,000 annual deaths are related to rheumatic heart disease (RHD) and its complications. Resource-limited areas account for the vast majority of cases, although outbreaks still occur in industrialized countries. GAS has several mechanisms to avoid phagocytosis, including prevention of opsonization and the use of surface proteins to block complement fixation. The mechanisms behind the immunologic phenomenon are not well understood. Clinical presentations range from benign, short-lived impetigo or pharyngitis through to lifelong RHD. In its most invasive form, GAS can cause a rapidly progressive, often lethal infection: streptococcal toxic shock syndrome. S. pyogenes remains universally sensitive to penicillin, which is the mainstay of treatment. Goto Sponge NotDistinct Permalink

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type	abstract
value	Abstract Group A Streptococcus (GAS) or Streptococcus pyogenes, affects an estimated 800 million people each year. Most of the resulting estimated 639,000 annual deaths are related to rheumatic heart disease (RHD) and its complications. Resource-limited areas account for the vast majority of cases, although outbreaks still occur in industrialized countries. GAS has several mechanisms to avoid phagocytosis, including prevention of opsonization and the use of surface proteins to block complement fixation. The mechanisms behind the immunologic phenomenon are not well understood. Clinical presentations range from benign, short-lived impetigo or pharyngitis through to lifelong RHD. In its most invasive form, GAS can cause a rapidly progressive, often lethal infection: streptococcal toxic shock syndrome. S. pyogenes remains universally sensitive to penicillin, which is the mainstay of treatment.
subject	Organisms Gastrointestinal tract disorders RTT RTTEM Adultery in films
part of	40 Group A Streptococcus
is abstract of	40 Group A Streptococcus
is hasSource of	covid:ann/target/e305c5d4222167d6fb86f482889161ce0bba512d covid:ann/target/b77872aff9756c8f9a1cc1c9a5ce0e6e219c1ac5 covid:ann/target/bbe805e08d76500303248bad519ff7801a6b67eb covid:ann/target/c07c6ad8648bf88f6d97a8041c7d806d62519c63 covid:ann/target/e2b29628a3db53c764f5c5fa470683d9aae39384 »more»

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