About: The impact of fluid balance on outcomes in premature neonates: a report from the AWAKEN study group

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	The impact of fluid balance on outcomes in premature neonates: a report from the AWAKEN study group
Creator	Goldstein, Stuart Akcan-Arikan, Ayse Askenazi, David Bonachea, Elizabeth Boohaker, Louis Gist, Katja Griffin, Russell Guillet, Ronnie Hanna, Mina Joseph, Catherine Mahan, John Mammen, Cherry Nada, Arwa Nathan, Amy Reidy, Kimberly Selewski, David Staples, Amy Wintermark, Pia
Source	PMC
abstract	BACKGROUND: We evaluated the epidemiology of fluid balance (FB) over the first postnatal week and its impact on outcomes in a multi-center cohort of premature neonates from the AWAKEN study. METHODS: Retrospective analysis of infants <36 weeks’ gestational age from the AWAKEN study (N = 1007). FB was defined by percentage of change from birth weight. Outcome: Mechanical ventilation (MV) at postnatal day 7. RESULTS: One hundred and forty-nine (14.8%) were on MV at postnatal day 7. The median peak FB was 0% (IQR: −2.9, 2) and occurred on postnatal day 2 (IQR: 1,5). Multivariable models showed that the peak FB (aOR 1.14, 95% CI 1.10–1.19), lowest FB in first postnatal week (aOR 1.12, 95% CI 1.07–1.16), and FB on postnatal day 7 (aOR 1.10, 95% CI 1.06–1.13) were independently associated with MV on postnatal day 7. In a similar analysis, a negative FB at postnatal day 7 protected against the need for MV at postnatal day 7 (aOR 0.21, 95% CI 0.12–0.35). CONCLUSIONS: Positive peak FB during the first postnatal week and more positive FB on postnatal day 7 were independently associated with MV at postnatal day 7. Those with a negative FB at postnatal day 7 were less likely to require MV.
has issue date	2019-09-19(xsd:dateTime)
bibo:doi	10.1038/s41390-019-0579-1
bibo:pmid	31537009
has license	no-cc
sha1sum (hex)	da162b50a55aa947c868e33a4ce43f0cc4ec88af
schema:url	https://doi.org/10.1038/s41390-019-0579-1
resource representing a document's title	The impact of fluid balance on outcomes in premature neonates: a report from the AWAKEN study group
has PubMed Central identifier	PMC7036003
has PubMed identifier	31537009
schema:publication	Pediatr Res
resource representing a document's body	covid:da162b50a55aa947c868e33a4ce43f0cc4ec88af#body_text
is schema:about of	named entity 'study' named entity 'postnatal' named entity 'RESULTS' named entity 'median' named entity 'postnatal' named entity 'Positive' named entity 'MEDIAN' named entity 'DAY 2' named entity 'METHODS' named entity 'OCCURRED' named entity 'negative' named entity 'postnatal' named entity 'postnatal' named entity 'neonates' named entity 'IQR' named entity 'peak' named entity 'negative' named entity '95% CI' named entity 'Neonatal' named entity 'birth weight' named entity 'epidemiology' named entity 'neonates' named entity 'fluid balance' named entity 'fluid balance' named entity 'mechanical ventilation' named entity 'gestational age' named entity 'critically ill' named entity 'urinary tract' named entity 'birth weight' named entity 'meta-analysis' named entity 'birth weight' named entity 'confidence intervals' named entity 'gestational age' named entity 'fluid balance' named entity 'fluid balance' named entity 'neonates' named entity 'postnatal' named entity 'fluid balance' named entity 'gestational age' named entity 'postnatal' named entity 'intravenous fluids' named entity 'fluid balance' named entity 'birth weight' named entity 'odds ratios' named entity 'fluid balance' named entity 'necrotizing enterocolitis' named entity 'postnatal' named entity 'neonates' named entity 'patent ductus arteriosus' named entity 'fluid balance' named entity 'neonates' named entity 'Logistic regression' named entity 'PDA' named entity 'mechanically ventilated' named entity 'postnatal' named entity 'congenital' named entity 'morbidity' named entity 'AKI' named entity 'enteral' named entity 'confounding variables' named entity 'AKI' named entity 'neonates' named entity 'regression models' named entity 'morbidity'

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