About: Epidemiology and microbiological investigations of community-acquired pneumonia in children admitted at the emergency department of a university hospital

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About: Epidemiology and microbiological investigations of community-acquired pneumonia in children admitted at the emergency department of a university hospital Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Epidemiology and microbiological investigations of community-acquired pneumonia in children admitted at the emergency department of a university hospital
Creator	Pillet, Sylvie Pozzetto, Bruno Bonneau, Julie Cantais, Aymeric Mory, Olivier Patural, Hugues Verhoeven, Paul
Source	Elsevier; Medline; PMC
abstract	BACKGROUND: The management of children with community-acquired pneumonia (CAP) is largely influenced by the development of new molecular diagnostic tests that allow the simultaneous detection of a wide range of pathogens. OBJECTIVES: Evaluation of a diagnostic approach including multiplex PCR assays for revisiting the epidemiology and etiology of CAP in children at hospital. STUDY DESIGN: Children of all ages consulting at the Emergency Department of the University hospital of Saint-Etienne, France, during the 2012–2013 winter period were included. In addition to bacterial cultures, the following pathogens were detected using biplex commercially-available rt-PCR tests: adenovirus, respiratory syncytial virus, human metapneumovirus, bocavirus, rhinovirus/enterovirus, coronavirus, influenza viruses A and B, parainfluenza viruses, Mycoplasma pneumoniae and Chlamydophila pneumonia. RESULTS: From 85 patients with CAP, at least one pathogen was identified in 81 cases (95.3%), including 4 bacterial exclusive infections (4.7%), 53 viral exclusive infections (62.4%) and 24 mixed infections (28.2%). Coinfection by at least two viruses was observed in 37 cases (43.5%). Mean age was higher in the case of documented bacterial infection (P < 0.05). In the subgroup of viral exclusive infection, the mean age of severe cases was 2.0 years vs 3.8 years in mild and moderate cases (P < 0.05). CONCLUSIONS: These findings highlight the huge proportion of CAP of viral origin, the high number of co-infection by multiple viruses and the low number of bacterial CAP, notably in children under 5 years, and address the need to re-evaluate the indications of empiric antimicrobial treatment in this age group.
has issue date	2014-05-22(xsd:dateTime)
bibo:doi	10.1016/j.jcv.2014.05.006
bibo:pmid	24915939
has license	no-cc
sha1sum (hex)	d95aa29fa61c9fd4ee5f7bc29fca44d9e124c517
schema:url	https://doi.org/10.1016/j.jcv.2014.05.006
resource representing a document's title	Epidemiology and microbiological investigations of community-acquired pneumonia in children admitted at the emergency department of a university hospital
has PubMed Central identifier	PMC7106426
has PubMed identifier	24915939
schema:publication	J Clin Virol
resource representing a document's body	covid:d95aa29fa61c9fd4ee5f7bc29fca44d9e124c517#body_text
is schema:about of	named entity 'INVESTIGATIONS' named entity 'age' named entity 'proportion' named entity 'subgroup' named entity 'development' named entity 'infections' named entity 'EMERGENCY DEPARTMENT' named entity 'THESE' named entity 'EPIDEMIOLOGY' named entity 'INFLUENZA VIRUSES' named entity 'BACTERIAL CULTURES' named entity 'FRANCE' named entity '0.05' named entity 'STUDY DESIGN' named entity 'VIRUSES' named entity 'OBSERVED' named entity 'HUMAN METAPNEUMOVIRUS' named entity 'EVALUATION' named entity 'CHLAMYDOPHILA PNEUMONIA' named entity 'INDICATIONS' named entity 'AGE GROUP' named entity 'COINFECTION' named entity 'ADDRESS' named entity 'UNIVERSITY HOSPITAL' covid:arg/d95aa29fa61c9fd4ee5f7bc29fca44d9e124c517 named entity 'MODERATE' named entity 'LARGELY' named entity 'MULTIPLEX PCR' named entity 'DETECTION' named entity 'WIDE' named entity 'DETECTED' named entity 'MULTIPLE' named entity 'HIGHER' named entity 'APPROACH' named entity '28P' named entity 'PERIOD' named entity 'DEVELOPMENT' named entity 'CONCLUSIONS' named entity 'HOSPITAL' named entity 'WINTER' named entity 'PARAINFLUENZA' named entity 'BIPLEX' named entity 'IDENTIFIED' named entity 'SEVERE' named entity 'BACTERIAL' named entity 'AGE' named entity 'NUMBER OF' named entity 'HUGE' named entity 'PATIENTS' named entity 'EMPIRIC' named entity 'LOW' named entity 'MIXED' named entity 'AVAILABLE' named entity 'NEW' named entity 'RT-PCR' named entity 'ETIOLOGY' named entity 'TESTS' named entity 'BACKGROUND' named entity 'ADENOVIRUS' named entity 'MANAGEMENT' named entity 'CORONAVIRUS' named entity 'DIAGNOSTIC TESTS' named entity 'RANGE' named entity 'PATHOGENS' named entity 'SAINT-ETIENNE' named entity 'VIRAL' named entity 'RESPIRATORY SYNCYTIAL VIRUS' named entity 'MILD' named entity 'INFECTIONS' named entity 'ALL AGES' named entity 'MYCOPLASMA PNEUMONIAE' named entity 'CONSULTING' named entity 'UNIVERSITY HOSPITAL' named entity 'COMMUNITY-ACQUIRED PNEUMONIA' named entity 'CHILDREN'

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